摘要
目的:探讨苓桂术甘汤联合常规西药治疗阳虚水泛型室性早搏的效果。方法:选取2021年1月-2022年1月于上海市中西医结合医院诊治的120例阳虚水泛型室性早搏患者,使用随机数字表法分为观察组及对照组,各60例。对照组接受常规西药治疗,观察组在对照组基础上加用苓桂术甘汤治疗。对比两组总有效率、中医症候积分、心功能指标、心律震荡指标。结果:观察组总有效率高于对照组(P<0.05)。治疗前,两组各项中医症候积分比较,差异均无统计学意义(P>0.05);治疗后,两组各项中医症候积分均降低,观察组均低于对照组(P<0.05)。治疗前,两组每搏量(SV)、左室射血分数(LVEF)及左心室短轴缩短率(LVFS)比较,差异均无统计学意义(P>0.05);治疗后,两组以上各项指标均上升,观察组均高于对照组(P<0.05)。治疗前,两组震荡斜率(TS)及震荡初始(TO)比较,差异均无统计学意义(P>0.05);治疗后,两组TS水平均升高,观察组高于对照组,TO均降低,观察组低于对照组(P<0.05)。结论:苓桂术甘汤联合常规西药治疗阳虚水泛型室性早搏效果显著,可有效缓解临床症状,改善心功能及心律震荡。
Objective:To investigate the effect of Ling Gui Zhu Gan Decoction combined with conventional western medicine in the treatment of Yang deficiency and water flooding type of premature ventricular beat.Method:A total of 120 patients diagnosed and treated with Yang deficiency and water flooding type of premature ventricular beat in Shanghai TCM-integrated Hospital from January 2021 to January 2022 were selected and divided into an observation group and a control group according to the random number table method,60 cases in each group.The control group received routine western medicine treatment,and the observation group was treated with Ling Gui Zhu Gan Decoction on the basis of the control group.The total effective rate,TCM symptoms scores,cardiac function indexes and heart rate turbulence indexes were compared between the two groups.Result:The total effective rate of the observation group was higher than that of the control group(P<0.05).Before treatment,there were no significant differences in each TCM symptom between the two groups(P>0.05).After treatment,the scores of each TCM symptom in the two groups decreased,and those in the observation group were lower than those in the control group(P<0.05).Before treatment,there were no significant differences in stroke volume(SV),left ventricular ejection fraction(LVEF)and left ventricular fractional shortening(LVFS)between the two groups(P>0.05).After treatment,all the above indexes of the two groups increased,and those in the observation group were higher than those in the control group(P<0.05).Before treatment,there were no significant differences in the turbulence slope(TS)and the turbulence onset(TO)between the two groups(P>0.05).After treatment,the TS in the two groups were increased,that in the observation group was higher than that in the control group,and the TO in the two groups were decreased,that in the observation group was lower than that in the control group(P<0.05).Conclusion:Ling Gui Zhu Gan Decoction combined with conventional western medicine has a remarkable effect in the treatment of Yang deficiency and water flooding type of premature ventricular beat,which can effectively relieve clinical symptoms and improve cardiac function and heart rate turbulence.
作者
庞瑜
张家美
俞瑞群
PANG Yu;ZHANG Jiamei;YU Ruiqun(Shanghai TCM-integrated Hospital,Shanghai 200082,China;不详)
出处
《中国医学创新》
CAS
2023年第12期67-71,共5页
Medical Innovation of China
关键词
室性早搏
阳虚水泛型
苓桂术甘汤
心功能
心律震荡
Premature ventricular beat
Yang deficiency and water flooding type
Ling Gui Zhu Gan Decoction
Cardiac function
Heart rate turbulence