摘要
目的:探讨经鼻高流量湿化氧疗用于慢性阻塞性肺疾病(COPD)患者的治疗效果。方法:选取2019年8月—2020年8月上海市松江区泗泾医院收治的78例COPD患者作为研究对象,根据随机数字表法分为常规组与观察组,各39例。常规组给予经鼻正压通气吸氧治疗,观察组给予经鼻高流量湿化氧疗,比较两组症状缓解时间、血气指标水平、生命体征指标水平、不良反应发生情况。结果:观察组咳嗽、喘憋、啰音缓解时间短于常规组,差异有统计学意义(P=0.0000)。治疗前,两组二氧化碳分压、动脉血氧分压、酸碱度(pH)值比较,差异无统计学意义(P>0.05);治疗后,观察组二氧化碳分压低于常规组,动脉血氧分压、pH值高于常规组,差异有统计学意义(P=0.0000)。治疗前,两组呼吸频率、心率、舒张压、收缩压比较,差异无统计学意义(P>0.05);治疗后,观察组呼吸频率、心率、舒张压、收缩压低于常规组,差异有统计学意义(P=0.0000)。观察组不良反应发生率低于常规组,差异有统计学意义(P=0.0227)。结论:COPD治疗中,经鼻高流量湿化氧疗的开展,能够使患者肺部功能、血气指标等得到显著改善,治疗安全性较高,治疗效果理想。
Objective:To explore the treatment effect of nasal high-flow humidified oxygen therapy in the patients with chronic obstructive pulmonary disease(COPD).Methods:From August 2019 to August 2020,78 patients with COPD admitted to Sijing Hospital of Songjiang District of Shanghai were selected as the study subjects.According to the random number table method,they were divided into conventional group and observation group,with 39 cases in each group.The conventional group was given nasal positive pressure ventilation oxygen therapy,and the observation group was given nasal high-flow humidified oxygen therapy.The symptom relief time,blood gas index level,vital sign index level,and adverse reaction occurrence between the two groups were compared.Results:The relief time of cough,wheezing and rales in the observation group was shorter than that in the conventional group,and the difference was statistically significant(P=0.0000).Before treatment,there was no significant difference in carbon dioxide partial pressure,arterial oxygen partial pressure and power of hydrogen(pH)value between two groups(P>0.05).After treatment,the partial pressure of carbon dioxide in the observation group was lower than that in the conventional group,and the partial pressure of arterial oxygen and pH value in the observation group were higher than those in the conventional group,and the difference was statistically significant(P=0.0000).Before treatment,there were no significant differences in respiratory rate,heart rate,diastolic blood pressure and systolic blood pressure between the two groups(P>0.05).After treatment,the respiratory rate,heart rate,diastolic blood pressure,and systolic blood pressure in the observation group were lower than those in the conventional group,and the differences were statistically significant(P=0.0000).The incidence of adverse reactions in the observation group was lower than that in the conventional group,and the difference was statistically significant(P=0.0227).Conclusion:In the treatment of COPD,the development of nasal high-flow humidified oxygen therapy can significantly improve the lung function and blood gas indexes of patients.The treatment safety is high and the curative effect is ideal.
作者
王小美
黄洁丽
张俊锋
陈爱军
Wang Xiao-mei;Huang Jie-li;Zhang Jun-feng;Chen Ai-jun(Emergency Department,Sijing Hospital of Songjiang District,Shanghai 201600,China)
出处
《中国社区医师》
2023年第9期61-63,共3页
Chinese Community Doctors
基金
松江区科学技术攻关项目(编号:19SJKJGG57)。
关键词
经鼻高流量湿化氧疗
慢性阻塞性肺疾病
血气指标
Nasal high-flow humidified oxygen therapy
Chronic obstructive pulmonary disease
Blood gas index
