摘要
目的了解丰台区老年人免费接种23价肺炎球菌多糖疫苗在新冠肺炎疫情期间预防相关疾病的效果和成本效益。方法采取1∶1配对原则,招募接种组和对照组各200人65周岁以上的本市户籍老年人,通过回顾性队列研究方法了解2019—2021年两组老人同期因细菌感染所致呼吸道症状就诊、住院和医疗费用支出情况,计算成本效益。结果接种组和对照组因呼吸道症状就诊率分别为6.00%和12.00%,细菌性肺炎发病率分别为1.00%和3.00%。两组老人呼吸道症状就诊率差异有统计学意义(χ^(2)=4.396,P<0.05),细菌性肺炎发病率、住院率差异无统计学意义(χ^(2)=2.041,P>0.05)。两组老人门诊费(Z=2.200)、直接医疗费用(Z=2.385)、交通费(Z=2.032)、总费用(Z=2.445)差异有统计学意义,P<0.05。总效益为105525.78元,成本效益比为4.12。结论北京市丰台区老年人接种23价肺炎球菌多糖疫苗有一定的成本效益,有效减少老年人群细菌感染引发的呼吸道症状就诊率,可通过观察进一步评估其长期保护效果和成本效益。
Objective To study the protective effect and cost-benefit of free 23-valent pneumococcal polysaccharide vaccination for elderly people in Fengtai District in preventing related diseases during COVID-19 epidemic.Methods A matching principle of a 1∶1 ratio was adopted to recruit 200 vaccinated and 200 control group who were elderly over 65 years of age and were registered in the city,and the cost-effectiveness was calculated by a retrospective cohort study method to understand the clinic visits,hospitalizations and medical expenses for respiratory symptoms due to bacterial infections in both groups during the same period from 2019 to 2021.Results The rate of clinic visits for respiratory diseases were 6.00%and 12.00%in the vaccinated group and the control group,respectively,and the incidence of bacterial pneumonia were 1.00%and 3.00%,respectively.The difference between the two groups of elderly people with respiratory symptoms statistically significant difference(χ^(2)=4.396,P<0.05),while the difference in the incidence of bacterial pneumonia and hospitalization rate was not statistically significant(χ^(2)=2.041,P>0.05).There were statistically significant differences between the two groups of the elderly in outpatient expenses(Z=2.200),direct medical expenses(Z=2.385),transportation expenses(Z=2.032)and total expenses(Z=2.445),P<0.05.The total benefit was 105525.78RMB yuan,and the benefit cost ratio(BCR)was 4.12.Conclusion The 23-valent pneumococcal polysaccharide vaccine in elderly people in Fengtai District,Beijing,China,is cost-effective and effective in reducing the rate of clinic visits for respiratory symptoms caused by bacterial infections in the elderly population,and the long-term protective effect and cost-effectiveness may be further evaluated by observation.
作者
毛雯雯
李靖琳
姜晓飞
张建军
谢俊卿
吕敏
MAO Wenwen;LI Jinglin;JIANG Xiaofei;ZHANG Jianjun;XIE Junqing;LV Min(Fengtai Center for Disease Prevention and Control,Beijing 100070,China;不详)
出处
《医学动物防制》
2023年第4期318-321,共4页
Journal of Medical Pest Control
基金
北京市卫生系统高层次卫生技术人才队伍建设专项经费(2022-3-021)
丰台区卫生计生系统科学研究项目(2019-125)。
关键词
65周岁以上老年人
肺炎球菌性疾病
肺炎球菌多糖疫苗
保护效果
成本效益
Elderly over 65 years of age
Pneumococcal disease
Pneumococcal polysaccharide vaccine
Protective effect
Cost-effectiveness
