摘要
中医药可从多方面调节免疫、弱化不良反应、改善肾功能,一定程度上可作为膜性肾病临床应用激素及免疫抑制剂前的选择。本文从名医经验及中医药干预膜性肾病的临床与实验研究进行综述,旨在讨论中医药对膜性肾病的治疗理念、方法及干预机制,推动临床及实验研究,更好地指导临床实践。梳理近几年中医药治疗膜性肾病的临床及实验研究进展。中医药多通路干预延缓肾脏纤维化、抗炎及抗氧化应激、修护足细胞,从而改善膜性肾病的病理损害。目前中医药治疗膜性肾病效果甚佳,但仍需大样本、长期研究数据支持,药物及组方机制也待深究。
Traditional Chinese medicine can regulate immunity,weaken adverse reactions,and improve renal function from various aspects,and to some certain extent,it can be used as the choice before the clinical application of hormones and immunosuppressants in membranous nephropathy.This article reviews the clinical and experimental research of famous doctors and the intervention of traditional Chinese medicine in membranous nephropathy,aiming to discuss the treatment concepts,methods and intervention mechanisms of traditional Chinese medicine for membranous nephropathy,promote clinical and experimental research,and better guide clinical practice.In recent years,the clinical and experimental research progress of traditional Chinese medicine in the treatment of membranous nephropathy is summarized.Multi-channel intervention of traditional Chinese medicine delays renal fibrosis,anti-inflammatory and oxidative stress,and repairs foot cells,thereby improving the pathological damage of membranous nephropathy.At present,the efficacy of traditional Chinese medicine in the treatment of membranous nephropathy is very good,but it still needs to be supported by large samples and long-term research data,and the drug and formulation mechanism need to be further studied.
作者
李婉雯
刘洋
李婉露
渠雅君
唐好知
郝娜
LI Wanwen;LIU Yang;LI Wanlu;QU Yajun;TANG Haozhi;HAO Na(The First Teaching Hospital of Tianjin University of Traditional Chinese Medicine National Clinical Research Center of Traditional Chinese Medicine Acupuncture and Moxibustion,Tianjin300382,China;College of Acupuncture and Moxibustion,Shaanxi University of Chinese Medicine,Shaanxi Province,Xianyang712046,China)
出处
《中国医药导报》
CAS
2023年第12期44-47,共4页
China Medical Herald
基金
国家自然科学基金青年科学基金资助项目(81904141)。
关键词
膜性肾病
中医药
辨证论治
实验研究
Membranous nephropathy
Chinese medicine
Treatment based on syndrome differentiation
Experimental study
