摘要
糖尿病肾脏疾病(diabetic kidney disease, DKD)是临床常见病与多发病, 严重危害人类健康。DKD患者常常并发贫血, 其贫血特点是:与非糖尿病相关肾脏疾病(non-DKD, NDKD)相比, 贫血发生更早、危害性更重, 认识不足, 贫血机制复杂, 防治更难。近年来国内外肾脏病学会或组织先后发布了慢性肾脏病(chronic kidney disease, CKD)肾性贫血诊治指南或共识, 但对DKD贫血的诊疗指导, 仍有提升的空间。为此, 中国病理生理学会肾脏病专业委员会牵头组织成立了以肾脏病专家为主体, 联合内分泌、心血管内科、血液科专家组成的DKD贫血共识专家组, 通过对DKD贫血管理与现状调研, 参考国内外文献及相关指南/共识, 结合专家经验, 形成该共识。该共识内容首先介绍了DKD患者贫血特点、DKD贫血的危害及相关机制, 然后对DKD贫血筛查、贫血纠正启动时机、药物选择与注意事项、铁剂应用、DKD患者输血等临床所关心的问题进行了讨论, 提出了诊疗建议并达成共识, 旨在进一步加强临床医师对DKD贫血的认识与管理, 提高我国DKD贫血患者的防治水平。
Diabetic kidney disease(DKD)is a common and frequent clinical disease,which seriously endangers human health.Renal anemia is often complicated in patients with DKD,which is characterized by earlier onset,less recognition,complex mechanisms,more difficult prevention and treatment than that in non-DKD.In recent years,nephrology societies or organizations in the world have issued guidelines or consensus for the diagnosis and treatment of renal anemia in chronic kidney disease.However,they are not enough for renal anemia in DKD.To this end,a expert consensus on administration of renal anemia in DKD was developed mainly by nephrologists and endocrinology,cardiovascular specialist as well as hematologist,organizing by Chinese Association of Pathophysiology,Society of Nephrology.This consensus was formed through investigating the management and current situation of anemia in DKD,analyzing recently relevant literature and guidelines/consensus in the world,combining with the experts'clinical experience.The consensus firstly introduces the characteristics,hazards and related mechanisms of anemia in patients with DKD,and then discusses the clinical concerns in diagnosis and treatments of anemia in DKD patients,such as screening,the timing of treatment initiation,the selection of therapeutic drugs,iron application and blood transfusion.The aim is to further strengthen the understanding and management of anemia in DKD and improve the prevention and treatment of anemia in DKD patients in China.
作者
中国病理生理学会肾脏病专业委员会糖尿病肾脏疾病贫血共识专家组
孙林
杨俊伟
Consensus Expert Group on Anemia in Diabetic Kidney Disease,Chinese Association of Pathophysiology,Society of Nephrology;Sun Lin;Yang Junwei(不详;Department of Nephrology,the Second Xiangya Hospital,Central South University,National Clinical Research Center for Metabolic Diseases,Changsha 410011,China;Nephrology Center,the Second Affliated Hospital of Nanjing Medical University,Nanjing 210011,China)
出处
《中华肾脏病杂志》
CAS
CSCD
北大核心
2023年第3期229-244,共16页
Chinese Journal of Nephrology
关键词
糖尿病
糖尿病肾病
贫血
管理
Diabetes mellitus
Diabetic nephropathies
Anemia
Management
