摘要
目的:探讨心脏康复规范化诊疗在慢性心力衰竭合并认知障碍患者(CIHF)中的应用效果。方法:选取2021年7月-2022年12月南通市5家医院收治的CIHF患者300例为研究对象,按照随机数字表法分为观察组和对照组,各150例。对照组给予规范药物治疗,观察组在对照组基础上给予规范化心脏康复治疗。比较两组患者临床指标[6 min步行距离(6MWD)、左室射血分数(LVEF)、血浆N末端B型利钠肽原(NT-proBNP)]、认知功能[蒙特利尔认知评估量表(MoCA)]、主要心血管不良事件(MACE)情况。结果:治疗后,两组患者6MWD、LVEF水平均升高,NT-proBNP水平均降低,观察组优于对照组,差异有统计学意义(P<0.05);6个月后,观察组MACE发生率低于对照组,差异有统计学意义(P=0.031);治疗后,观察组MoCA评分高于治疗前,观察组高于对照组,差异有统计学意义(P<0.05)。结论:心脏康复规范化诊疗能够有效提高CIHF患者的心功能,减少心血管不良事件发生率,改善患者认知水平。
Objective:To explore the application effect of standardized diagnosis and treatment of cardiac rehabilitation in patients with cognitive impairment in chronic heart failure(CIHF).Methods:A total of 300 patients with CIHF admitted to 5 hospitals in Nantong City from July 2021 to December 2022 were selected as the study subjects.They were divided into the observation group and the control group according to random number table method,with 150 patients in each group.The control group was given standard drug treatment and the observation group was given standardized cardiac rehabilitation treatment on the basis of the control group.The clinical indexes[6 min walk distance(6MWD),left ventricular ejection fraction(LVEF),plasma N-terminal Btype natriuretic peptide(NT-proBNP)],cognitive function[Montreal Cognitive Assessment(MoCA)],and major adverse cardiovascular events(MACE)were compared between the two groups.Results:After treatment,the 6MWD and LVEF levels in both groups increased,and the levels of NT-proBNP decreased,and the observation group was better than the control group,and the difference was statistically significant(P<0.05).After 6 months,the incidence of MACE in the observation group was lower than that in the control group,and the difference was statistically significant(P=0.031).After treatment,the MoCA score in the observation group was higher than that before treatment,and the observation group was higher than the control group,and the difference was statistically significant(P<0.05).Conclusion:The standardized diagnosis and treatment of cardiac rehabilitation can effectively improve the cardiac function of patients with CIHF,reduce the incidence of adverse cardiovascular events,and improve the cognitive level of patients.
作者
邱祖红
潘海燕
陆袁洲
王为群
张锋
邱炜佳
Qiu Zu-hong;Pan Hai-yan;Lu Yuan-zhou;Wang Wei-qun;Zhang Feng;Qiu Wei-jia(Department of Cardiology,Nantong Tongzhou People's Hospital,Nantong 226300,Jiangsu Province,China)
出处
《中外医药研究》
2022年第17期49-51,共3页
JOURNAL OF CHINESE AND FOREIGN MEDICINE AND PHARMACY RESEARCH
关键词
心脏康复
认知障碍
慢性心力衰竭
Cardiac rehabilitation
Cognitive impairment
Chronic heart failure
