摘要
目的系统性评估美沙拉秦治疗溃疡性结肠炎的有效性和安全性。方法72例溃疡性结肠炎患者,随机分为观察组和对照组,每组36例。对照组利用柳氮磺吡啶治疗,观察组利用美沙拉秦治疗。比较两组临床疗效和不良反应发生率。结果观察组治疗总有效率100.00%高于对照组的80.56%,差异有统计学意义(P<0.05)。观察组不良反应发生率2.78%低于对照组的22.22%,差异有统计学意义(P<0.05)。结论以美沙拉秦治疗溃疡性结肠炎可以在保证安全的前提之下提升临床治疗效果,是值得推荐的一种治疗手段。
Objective To systematically evaluate the effectiveness and safety of mesalazine in the treatment of ulcerative colitis.Methods A total of 72 patients with ulcerative colitis were randomly divided into observation group and control group,with 36 cases in each group.The control group was treated with sulfasalazine,and the observation group was treated with mesalazine.The clinical efficacy and incidence of adverse reactions were compared between the two groups.Results The total effective rate of 100.00%in the observation group was higher than that of 80.56%in the control group,and the difference was statistically significant(P<0.05).The incidence of adverse reactions in the observation group was 2.78%,which was lower than that of 22.22%in the control group,and the difference was statistically significant(P<0.05).Conclusion The treatment of ulcerative colitis with mesalazine can improve the clinical effect under the premise of ensuring safety,and is a treatment method worthy of recommendation.
作者
郑丽丽
ZHENG Li-li(Second Department of Gastroenterology,Xinhua Hospital Affiliated to Dalian University,Dalian 116021,China)
出处
《中国实用医药》
2023年第8期117-119,共3页
China Practical Medicine
