摘要
目的 探究儿童急性呼吸道支原体感染与副流感病毒感染的血小板、白细胞、红细胞水平差异及其相关性。方法 回顾性分析2018年2月至2019年2月就诊的287例感染性疾病患儿的临床资料,依据其不同感染类型分为支原体感染组(136例)与副流感病毒感染组(151例),另选取同期来本院进行健康体检的100例患儿作为健康对照组。对比不同组别患儿血小板(PLT)、白细胞(WBC)、红细胞(RBC)水平差异。采用Pearson相关性分析PLT、WBC、RBC水平与支原体感染及副流感病毒感染的关系,通过受试者工作特征曲线(ROC曲线)分析PLT、WBC、RBC水平对区分支原体感染与副流感病毒感染的诊断价值。结果 支原体感染组PLT、WBC水平显著高于副流感病毒感染组与健康对照组,RBC水平低于副流感病毒感染组与健康对照组;副流感病毒感染组PLT高于健康对照组,RBC水平低于健康对照组,均P<0.05;支原体感染与PLT、WBC显著正相关,与RBC显著负相关,P<0.05;副流感病毒感染与PLT显著正相关,与RBC显著负相关,P<0.05;PLT、WBC、RBC及联合因子诊断支原体感染与副流感病毒感染的敏感度依次为69.1%、69.1%、89.7%、95.6%,P<0.05。结论 儿童支原体感染与副流感病毒感染在PLT、WBC、RBC水平上存在显著差异,通过联合PLT、WBC、RBC指标进行检测有利于对支原体感染与副流感病毒感染进行区分。
Objective To explore the differences and correlations of platelet,leukocyte and erythrocyte levels between acute respiratory mycoplasma infection and parainfluenza virus infection in children.Methods The clinical data of 287 children with infectious diseases admitted to our hospital from February 2018 to February 2019 were retrospectively analyzed,and they were divided into mycoplasma infection group(136 cases)and parainfluenza virus infection group(151 cases)according to their different infection types,and another 100 children who came to our hospital for physical examination during the same period were selected as the healthy control group.The differences in platelet(PLT),white blood cell(WBC),and red blood cell(RBC)levels of children in different groups were compared.Pearson correlation was used to analyze the relationship between the levels of PLT,WBC,and RBC with mycoplasma infection and parainfluenza virus infection.The receiver operating characteristic curve was used to analyze the diagnostic value of PLT,WBC,and RBC levels in differentiating mycoplasma infection and parainfluenza virus infection.Results The levels of PLT and WBC in mycoplasma infection group were significantly higher than those in parainfluenza virus infection group and healthy control group,while the levels of RBC were lower than those in parainfluenza virus infection group and healthy control group.PLT in parainfluenza virus infection group was higher than that in healthy control group,and RBC level was lower than that in healthy control group,both P<0.05.Mycoplasma infection was positively correlated with PLT and WBC,and negatively correlated with RBC,P<0.05.Parainfluenza virus infection was positively correlated with PLT and negatively correlated with RBC,P<0.05.The sensitivity of PLT,WBC,RBC and combined factors to diagnose mycoplasma infection and parainfluenza virus infection was 69.1%,69.1%,89.7%and 95.6%respectively,P<0.05.Conclusion There were significant differences in PLT,WBC and RBC levels between mycoplasma infection and parainfluenza virus infection in children.Combining PLT,WBC and RBC indicators was helpful to distinguish mycoplasma infection from parainfluenza virus infection.
作者
葛丽霞
GE Lixia(Department of Pediatrics,Emergency General Hospital,Beijing 100028,China)
出处
《中国优生与遗传杂志》
2023年第4期849-853,共5页
Chinese Journal of Birth Health & Heredity
关键词
儿童急性呼吸道支原体感染
副流感病毒感染
血小板
白细胞
红细胞
相关性分析
acute respiratory mycoplasma infection in children
parainfluenza virus infection
platelets
white blood cells
red blood cells
correlation analysis
