摘要
目的探讨全血中心肌肌钙蛋白I(cTnI),肌酸激酶同工酶-MB(CK-MB),肌红蛋白(Myo)和B型脑钠肽前体(NT-proBNP)的联合检测在急性心肌梗死诊断中的应用价值。方法选取河南省人民医院确诊为急性心肌梗死(AMI)的病人102例设为实验组,另外选取健康人102例,设为对照组。检测两组受试者全血中cTnI,Myo,CK-MB及NT-proBNP的表达,对比两组的结果,并对比联合检测和单项检测的结果。结果实验组的cTnI,Myo,CK-MB及NT-proBNP的表达均高于对照组(P<0.05),且这些指标的联合检测阳性率高于单项检测。结论急性心肌梗死的患者全血中cTnI,Myo,CK-MB及NT-proBNP的联合检测有利于提高疾病诊断的准确率,值得在临床推广。
Objective To explore the value of cardiac troponin I(cTnl),creatine kinase isoenzyme-MB(CK-MB),myoglobin(Myo)and B brain natriuretic peptide precursor(NT-proBNP)in the diagnosis of acute myocardial infarction.Methods 102 patients diagnosed with acute myocardial infarction(AMI)were selected as the experimental group,and 102 healthy patients were selected as the control group.The expression of cTnl,Myo,CK-MB and NT-proBNP in whole blood was compared the results and the results of the combined and individual tests.Results The expression of cTnI,Myo,CK-MB and NT-proBNP in the experimental group was higher than that in the control group(P<0.05),and the positive rate of these indexes was higher than that of the individual test.Conclusion The combined detection of cTnI,Myo,CK-MB and NT-proBNP in whole blood of patients with acute myocardial infarction is beneficial to improve the accuracy of disease diagnosis and should be worth popularizing in clinical practice.
作者
万震
田文倩
范砚茹
WAN Zhen;TIAN Wen-qian;FAN Yan-ru(Henan Provincial Peoples Hospital,Zhengzhou 450000,China)
出处
《医药论坛杂志》
2023年第5期106-109,共4页
Journal of Medical Forum
