摘要
目的 探讨呼吸康复对哮喘患儿吸气肌肌力、运动能力、肺功能、哮喘控制水平和生存质量的影响。方法 选择2021年6月至2022年2月于呼吸科门诊就诊的哮喘患儿,运用随机数字表将其随机分为试验组与对照组。对照组予以常规药物治疗及健康教育,试验组在此基础上联合呼吸康复,观察其对哮喘患儿的影响。结果 纳入57例哮喘患儿,均完成6个月试验,男38例、女19例,平均年龄(9.4±2.3)岁,平均病程4.0(2.1-5.5)年。试验组31例、对照组26例。进行6个月训练后,试验组最大口腔吸气压平均值和最大值、6分钟步行距离、哮喘控制水平高于对照组,6分钟步行后心率和生存质量得分低于对照组,差异有统计学意义(P<0.05),但两组步行后血压和肺功能差异无统计学意义(P>0.05)。进行6个月训练后,试验组最大口腔吸气压平均值和最大值,6分钟步行距离,肺功能[用力肺活量(FVC)、第一秒用力呼气容积(FEV_(1))、呼气峰流速(PEF)、75%和50%肺活量时的最大呼气流速(MEF_(75)、MEF_(50))、用力呼气中期流速(MMEF_(75/25))],哮喘控制水平高于干预前,6分钟步行后心率、收缩压和生存质量得分低于干预前;对照组最大口腔吸气压平均值和肺功能(FEV_(1)、FEV_(1)/FVC、MEF_(75)、MEF_(50)、MEF_(25)、MMEF_(75/25))高于干预前,差异均有统计学意义(P<0.05)。结论 在规范化治疗的基础上结合呼吸康复能改善哮喘患儿的吸气肌肌力、运动能力、哮喘控制水平和生存质量,且具有良好的安全性,临床工作者可将呼吸康复应用于哮喘患儿以期获得更好的疗效。
Objective To investigate the effect of respiratory rehabilitation on inspiratory muscle strength,exercise capacity,pulmonary function,asthma control level and quality of life in children with asthma.Methods The children with asthma treated in respiratory outpatient department from June 2021 to February 2022 were selected and randomly divided into experimental group and control group using a random number table.The control group was given routine drug treatment and health education,while the experimental group was combined with respiratory rehabilitation to observe its effects on children with asthma.Results A total of 57 children with asthma were included,all completed the 6-month experiment.There were 38 boys and 19 girls,with the average age of(9.4±2.3)years and the average disease course of 4.0(2.1-5.5)years.There were 31 children in the experimental group and 26 children in the control group.After 6 months of training,the mean and maximum values of maximum oral inspiratory pressure,6-minute walking distance,and asthma control level in the experimental group were higher than those in the control group(P<0.05),and the heart rate and quality of life scores after 6-minute walking were lower than those in the control group(P<0.05),but there was no significant difference in blood pressure and pulmonary function between the two groups(P>0.05).After 6 months of training,the mean and maximum values of maximum oral inspiratory pressure,6-minute walking distance,lung function(FVC,FEV_(1),PEF,MEF_(75),MEF_(50),MMEF_(75/25)),asthma control level in the experimental group were higher than those before the intervention(P<0.05),heart rate,systolic blood pressure and quality of life scores in the experimental group were lower than before the intervention(P<0.05),the mean value of maximum oral inspiratory pressure and pulmonary function(FEV_(1),FEV_(1)/FVC,MEF_(75),MEF_(50),MEF_(25),MMEF_(75/25))in the control group were higher than those before the intervention(P<0.05).Conclusions Combining respiratory rehabilitation with standardized treatment can improve inspiratory muscle strength,exercise capacity,asthma control level and quality of life in children with asthma,and has good safety.Clinicians can apply respiratory rehabilitation to asthma patients in order to obtain better curative effect.
作者
杨姝晖
刘玉琳
杨帆
罗征秀
刘恩梅
YANG Shuhui;LIU Yulin;YANG Fan;LUO Zhengxiu;LIU Enmei(Department of Respiratory Disease,Children's Hospital of Chongqing Medical University,Ministry of Education Key Laboratory of Child Development and Disorders,National Clinical Research Center for Child Heath and Disorders,China International Science and Technology Cooperation Base of Child Development and Critical Disorders,Chongqing Key Laboratory of Pediatrics,Chongqing 401120,China)
出处
《临床儿科杂志》
CAS
CSCD
北大核心
2023年第5期345-352,共8页
Journal of Clinical Pediatrics
基金
重庆市科卫联合医学科研项目(No.2021MSXM340)。
关键词
支气管哮喘
呼吸康复
肺功能
生存质量
儿童
bronchial asthma
respiratory rehabilitation
lung function
quality of life
child
