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急性前循环大血管闭塞性轻型卒中血管内治疗的疗效分析

Effects of endovascular treatment for mild stroke patients with acute anterior circulation large vessel occlusion
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摘要 目的分析急性前循环大血管闭塞性轻型卒中患者接受血管内治疗的疗效及安全性。方法回顾性分析2018年1月至2021年8月就诊于西安交通大学第一附属医院的38例接受血管内治疗的急性前循环大血管闭塞性轻型卒中患者的临床资料,观察患者术后血管再通率(mTICI分级≥2b)、围手术期并发症、出院时NIHSS评分变化及90 d良好预后率(mRS评分≤2)。结果38例患者平均年龄为(62.89±12.41)岁,其中男性21例(55.3%),术后血管成功再通率为100%,血栓逃逸3例(7.9%),术后24 h症状性颅内出血1例(2.6%)。出院时NIHSS评分平均1分(0~1分)较术前NIHSS评分平均4分(4~5分)比较具有统计学差异(P<0.01),90 d临床及影像学随访率89.47%,预后良好(mRS评分≤2分)比例为91.2%,影像学随访评估病变血管通畅性良好,支架置入患者未发生支架内再狭窄,临床随访期间无新发脑血管事件及死亡。结论急性前循环大血管闭塞性轻型卒中接受血管内治疗可能是安全及有效的。 Objective To observe the safety and effectiveness of endovascular treatment for mild stroke patients with acute anterior circulation large vessel occlusion.Methods The retrospective study enrolled 38 mild stroke patients with anterior circulation large vessel occlusion who received endovascular thrombectomy(EVT)at The First Affiliated Hospital of Xi’an Jiaotong University between January 2018 and August 2021.Vascular recanalization rate after endovascular treatment(mTICI≥2b),procedural complications,NIHSS score at discharge,and the rate of good modified Rankin Score(mRS≤2)at 90d were observed.Results The average age of the 38 patients was 62.89±12.41 years,and there were 21 males(55.3%).The vascular recanalization rate post EVT was 100%,while with three cases of thrombosis escape(7.9%)and one case(2.6%)of sICH of 24 h post EVT.The average NIHSS at discharge was 1(0-1)point,which significantly decreased compared to the average baseline NIHSS 4(4-5)points(P<0.01).The 90 d followed-up rate was 89.47%,and among all the followed-up patients,91.2%of them had mRS≤2.Imaging follow-up showed good vascular flow and no in-stent restenosis.Conclusion Endovascular treatment for acute anterior circulation large vessel occlusion in mild stroke is safe and effective.
作者 王建懿 商苏杭 陈晨 于嘉 韩建峰 刘福德 WANG Jianyi;SHANG Suhang;CHEN Chen;YU Jia;HAN Jianfeng;LIU Fude(Department of Neurology,The First Affiliated Hospital of Xi’an Jiaotong University,Xi’an 710061,China)
出处 《西安交通大学学报(医学版)》 CAS CSCD 北大核心 2023年第3期427-431,共5页 Journal of Xi’an Jiaotong University(Medical Sciences)
基金 西安交通大学第一附属医院青年基金(No.2020QN-14)。
关键词 前循环大血管闭塞 轻型卒中 血管内治疗 疗效 anterior circulation large vessel occlusion mild stroke endovascular treatment efficacy
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