摘要
目的 分析DWI联合DCE-MRI对于孤立肺结节(SPN)良恶性的鉴别诊断价值。方法 选取本院47名SPN患者,男:30例,女:17例,年龄:29~86岁,平均年龄:58±5.62岁。行常规DWI与DCEMRI扫描。比较良性组与恶性组ADC、K^(trans)、K_(ep)、V_(e)和iAUC值。采用受试者ROC曲线以评估其诊断效能。结果 对于K^(trans)、Ve与iAUC值,恶性组显著高于良性组(P<0.035),ADC值恶性组显著低于良性组(P=0.001)。对于K_(ep)值,两组间未见明显差异性(P=0.06)。而ADC联合iAUC分析其灵敏度可提高到81.8%,特异性提高到86.7%,准确度提高到83.8%。结论 采用常规DWI联合DCE-MRI进行定量分析SPN,可提高MR在SPN良恶性鉴别中的诊断效能。
Objective To analyze the value of DWI combined with DCE-MRI in the differential diagnosis of benign and malignant solitary pulmonary nodules(SPN).Methods Selected 47 SPN patients in our hospital,male:30 cases,female:17 cases,age:29-86 years old,average age:58±5.62 years old.Routine DWI and DCE-MRI scans were performed.The ADC,K^(trans),Kep,V_(e) and iAUC values of benign and malignant groups were compared.The subject ROC curve was used to evaluate its diagnostic performance.Results For K^(trans),V_(e) and iAUC values,the malignant group was significantly higher than the benign group(P<0.035),and the ADC value of the malignant group was significantly lower than that of the benign group(P=0.001).For the Kep value,no significant difference was found between the two groups(P=0.06).The ADC combined with iAUC analysis can improve the sensitivity to 81.8%,the specificity to 86.7%,and the accuracy to 83.8%.Conclusion Conventional DWI combined with DCE-MRI to quantitatively analyze SPN can improve the diagnostic performance of MR in distinguishing benign from malignant SPN.
作者
汪汉林
李自凯
梁奕
王佳
范文辉
WANG Han-lin;LI Zi-kai;LIANG Yi;WANG Jia;FAN Wen-hui(Department of Radiology,General Hospital of the Yangtze River Shipping•Wuhan Brain Hospital,Wuhan 430014,Hubei Province,China)
出处
《中国CT和MRI杂志》
2023年第5期37-39,共3页
Chinese Journal of CT and MRI
基金
湖北省卫生健康委员会科研课题(WJ2019H373)
武汉市卫生健康委员会科研课题(WX19Q26)
长江航务管理局重点科技项目(201910022)。
