摘要
目的探讨吴江地区孕产妇乙型肝炎病毒的感染和免疫保护状况,为重点人群乙肝的预防和控制提供科学依据。方法选取在本地区各医院进行初次产前检查,并有完整产检和分娩信息的7766例孕产妇作为研究对象,初次产检时对孕妇抽取的血清样本进行乙肝两对半(五项指标)检测,并进行部分肝功能指标的检测,对各项检测结果进行分类统计。结果各年龄段孕产妇乙肝表面抗原(HBsAg)阳性率经比较,随孕产妇年龄增长HBsAg阳性率逐渐升高;本省户籍组HBsAg阳性率为2.12%低于非本省户籍组的4.08%,肝功能异常组的HBsAg阳性率为12.82%高于肝功能正常组的3.00%,差异有统计学意义(P<0.05)。结论本地区孕产妇乙肝病毒携带率仍较高,乙肝免疫保护程度较低,需要做好孕产妇乙型肝炎病毒的早期筛查工作,可针对HBsAg阳性的孕产妇及时采取正确有效的干预措施,以改善预后。
Objective To explore the status of hepatitis B virus infection and immune protection in pregnant women in Wujiang district,and to provide scientifi c basis for the prevention and control of hepatitis B in key population.Methods A total of 7766 pregnant women who underwent the fi rst prenatal examination in various hospitals in the region and had complete information of the birth examination and delivery were selected as the research objects.During the fi rst prenatal examination,the serum samples taken by the pregnant women were tested for two-half hepatitis B(fi ve indicators),and some liver function indicators were tested,and the test results were classifi ed and statistically analyzed.Results The positive rate of hepatitis B surface antigen(HBsAg)in pregnant women of different ages was compared,and the positive rate of HBsAg increased gradually with the age of pregnant women.The positive rate of HBsAg in provincial household registration group(2.12%)was lower than that in the non-provincial household registration group(4.08%).The positive rate of HBsAg in the abnormal liver function group(12.82%)was higher than that in the normal liver function group(3.00%),and the difference was statistically significant(P<0.05).Conclusion The hepatitis B virus carrying rate of pregnant women in this region is still high,hepatitis B immune protection degree is low,do a good job in the early screening of hepatitis B virus in pregnant women is needed,which can take correct and effective intervention measures for HBsAg positive pregnant women in time,in order to improve the prognosis.
作者
朱晓燕
Zhu Xiaoyan(Department of Women's Health Section,Suzhou Wujiang District Maternal and Child Health and Family Planning Service Center,Suzhou,Jiangsu 215200,China)
出处
《实用妇科内分泌电子杂志》
2022年第33期78-80,共3页
Electronic Journal of Practical Gynecological Endocrinology
关键词
乙型肝炎病毒
乙肝表面抗原
孕产妇
母婴传播
Hepatitis B virus
Hepatitis B surface antigen
Pregnant women
Mother-to-child transmission
