摘要
帕金森病(PD)是中老年人最常见的第二大神经退行性疾病。PD除了运动症状以外,还有许多非运动症状,比如嗅觉障碍、便秘、认知障碍等,其中,嗅觉障碍是早期PD的一种常见非运动症状。研究已证实,嗅觉障碍可出现于PD的典型临床症状之前,对疾病的诊治有着重要的意义。但目前有关嗅觉障碍的发病机制尚不清楚,检查手段也尚未统一,也没有完全治愈的手段。本文就PD嗅觉障碍的最新研究进展作一综述。
Parkinson's disease(PD)is the second most common neurodegenerative disease in middle-aged and elderly people.In addition to motor symptoms,PD also has many non motor symptoms,such as dysosmia,constipation,cognitive impairment,etc.Among them,dysosmia is a common non motor symptom of early Parkinson's disease.Research has confirmed that olfactory dysfunction(OD)can appear before the typical clinical symptoms of PD,which is of great significance to the diagnosis and treatment of diseases.However,at present,the pathogenesis of OD is still unclear,and the inspection methods have not been unified,and there is no complete cure.This article reviews the latest research progress of dysosmia in Parkinson's disease.
作者
许文帝
陈涛
杨强
曾聃婷
李习
钟丽凡
蔡奔驰
Xu Wendi;Chen Tao;Yang Qiang;Zeng Danting;Li Xi;Zhong Lifan;Cai Benchi(Department of Neurology,Hainan Provincial People's Hospital,Haikou 570311,China)
出处
《中国医师杂志》
CAS
2023年第4期622-626,共5页
Journal of Chinese Physician
基金
国家重点研发计划(2020YFC2006400,2020YFC2006404)
海南省自然科学基金(820RC759)
海南省教改重点项目(Hnjg2019ZD-15)。
关键词
帕金森病
嗅觉障碍
Parkinson disease
Olfaction disorders
