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肠道微生物群与代谢相关性脂肪性肝病关系的研究进展 被引量：3

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摘要 代谢相关性脂肪性肝病(MAFLD)在全球普遍流行,经过脂质超载、内质网应激、线粒体功能障碍、氧化应激等“多重打击”,由肝脏脂肪积聚发展为非酒精性脂肪性肝炎(NASH),最终发展为MAFLD相关性肝细胞癌(MAFLD-HCC)。肠内微生物群被称为人类第二基因组,通过肠-肝轴与肝脏双向相关。本文对肠道微生物群失调与MAFLD发病之间关系的研究进展进行综述,旨在为MAFLD的临床防治提供参考。
作者 张珂瓈 李昌平
机构地区 西南医科大学临床医学院 西南医科大学附属医院消化内科
出处 《现代临床医学》 2023年第3期223-225,229,共4页 Journal of Modern Clinical Medicine
关键词 肠道微生物群 代谢相关性脂肪性肝病 肠-肝轴 多重打击
分类号 R575 [医药卫生—消化系统]
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现代临床医学
2023年 第3期

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