摘要
目的:探索古籍中多寐的病因病机特点及用药规律。方法:搜索历代古籍中对多寐的相关论述及治疗方剂,采用Excel及SPSS 21.0统计软件对多寐的病因病机及中药性、味、归经等进行频数和聚类分析。结果:1)古籍条文中多寐的病因病机主要有热邪伤阴、卫气滞阴、脾病湿困、胆热肝实、心虚神乱、阴病阳虚等;2)中药药性以温、寒为主,药味以辛、甘、苦为主,归经以脾、胃、肝、肺、肾为主,使用频率较高的核心药物有人参、甘草、茯苓、白术、陈皮等24味;3)共得到4组药物聚类分析组合,C1:丁香、肉豆蔻、干姜、木香、肉桂、附子;C2:神曲、麦芽、陈皮、苍术、白术、厚朴;C3:当归、黄芪、五味子、升麻、白芍、麦冬;C4:人参、茯苓、半夏、酸枣仁。结论:古代医家治疗多寐多以脾胃为病机核心,涉及气、血、阴、阳及湿邪等多种病理证素。
Objective:To explore the cause,pathogenesis and medication rules of somnolence in the ancient books.Methods:After searching the relevant statement and the prescriptions of somnolence in the ancient books,Excel and SPSS 21.0 statistical software were used to carry out frequency and cluster analysis of the cause and the pathogenesis of somnolence,the nature,flavor and meridian tropism of herbs.Results:1)In the articles of ancient books,the cause and the pathogenesis of somnolence mainly were heat pathogen hurting Yin,defensive-Qi stagnating Yin,dampness encumbering due to the disease of spleen,heat in the gallbladder and excess in the liver,cardiac deficiency and delirium,and Yin disease due to Yang deficiency;2)the medicine of TCM was primarily warm and cold,with the pungent,sweet and bitter flavor,entering the meridians of spleen,stomach,liver,lung and kidney,the core herbs with higher frequency were 24 ones including ginseng,Gancao(Glycyrrhizae radix et rhizoma),Fuling[Poria cocos(Schw.)Wol],Baizhu(Atractylodes macrocephala Koidz.)and Chenpi(Citrus reticulata Blanco);3)Four sets of drug combination of cluster analysis were obtained,C1:Dingxiang(Caryophylli flos),Roudoukou(Myristicae semen),dried ginger,Muxiang(Aucklandiae radix),Rougui(Cinnamomi cortex),Fuzi(Aconiti lateralis radix praeparata);C2:Shenqu(medicated leaven),Maiya(Hordei fructus germinatus),Chenpi(Citrus reticulata Blanco),Cangzhu(Atractylodis rhizoma),Baizhu(Atractylodes macrocephala Koidz.);C3:Danggui(Angelicae sinensis radix),Huangqi(Astragali radix),Wuweizi(Schisandrae chinensis fructus),Shengma(Cimicifugae rhizoma),Baishao(Paeoniae radix alba),Maidong(Ophiopogonis radix);C4:ginseng,Fuling,Banxia(Pinelliae rhizoma)and Suanzaoren(Ziziphi spinosae semen).Conclusion:Ancient doctors mostly take spleen and stomach as the core of the pathogenesis in the treatment of somnolence,involving many kinds of pathological syndrome elements:Qi,blood,Yin,Yang and damp evil.
作者
罗乐
孙书臣
谢瑛
LUO Le;SUN Shuchen;XIE Ying(Guang'anmen Hospital,China Academy of Chinese Medical Sciences,Beijing 100029,China;Beijing Friendship Hospital Affiliated to Capital Medical University,Beijing 100050,China)
出处
《西部中医药》
2023年第5期68-71,共4页
Western Journal of Traditional Chinese Medicine
基金
北京市自然科学基金(7162049)。
关键词
多寐
病因病机
用药规律
聚类分析
古籍
somnolence
the cause and pathogenesis
medication laws
cluster analysis
ancient books
