摘要
目的评价超声引导下经皮穿刺聚多卡醇硬化治疗儿童甲状舌管囊肿的有效性及安全性。方法回顾性分析2019年10月至2022年4月在首都医科大学附属北京儿童医院接受超声引导下经皮穿刺硬化治疗甲状舌管囊肿的患儿26例,记录治疗前囊肿的大小,并按照V(ml)=1/6πabc计算囊肿体积。随访时间为术后第1、3、6、12个月,记录不同时间点囊肿体积并计算体积缩小率,以囊肿体积缩小率≥50%为治疗有效。对治疗前及治疗后末次随访时进行外观美容分级评分。随访期间记录有无并发症发生。结果治疗前囊肿体积为2.67(3.78)ml,治疗后第1、3、6、12个月囊肿体积分别为0.66(1.83)、0.45(0.87)、0.40(0.70)、0.38(0.63)ml,术后各时间点与术前比较差异有统计学意义(均P<0.001),末次随访时体积缩小率为(81.48±14.57)%。22例患儿末次随访时囊肿体积缩小率超过50%,治疗有效率为84.62%(22/26)。治疗后美观评分为1.74(1.50)分,较治疗前评分[3.85(0)]分明显改善(P<0.001)。所有患儿均未发生皮肤色素沉着、注射区疼痛、局部荨麻疹、硬化后局部水疱、囊肿出血、醉酒样反应等不良反应;2例患儿随访期间出现感染伴发热,无严重并发症发生。结论超声引导经皮穿刺硬化治疗对儿童甲状舌管囊肿是一种微创、安全有效的治疗方法。
Objective To evaluate the effectiveness and safety of ultrasound-guided percutaneous polidocanol sclerotherapy of the thyroglossal duct cysts in children.Methods A retrospective analysis of 26 children who were treated with ultrasound-guided percutaneous puncture sclerosis for thyroglossal duct cysts in Beijing Children′s Hospital,Capital Medical University from October 2019 to April 2022,the size of the cyst before treatment was recorded,and the cyst volume in accordance with V(ml)=1/6πabc cyst volume was calculated.The follow-up time was the 1st,3rd,6th,and 12th months after sclerotherapy.And the cyst volume and volume reduction ratio at different time points was calculated.According to changes in the cystic volume,the treatment was considered effective if the cyst volume reduction rate was≥50%.Cosmetic grading scores(CGS)were performed pre-treatment and at the last follow-up after sclerotherapy using the WHO grading system.Complications were recorded during the follow-up period.Results The cyst volume before treatment was 2.67(3.78)ml,and the cyst volume at the 1st,3rd,6th and 12th month after treatment were 0.66(1.83),0.45(0.87),0.40(0.70),0.38(0.63)ml,respectively,there were significant differences between pre-treatment and each time point after-treatment(all P<0.001);the volume reduction rate at the last follow-up was(81.48±14.57)%.The reduction rate of cyst volume was more than 50%at the last follow-up in 22 children,the treatment efficiency was 84.62%(22/26).The cosmetic grading scores at the last follow-up after sclerotherapy was 1.74(1.50),and it decreased significantly compared with the pre-treatment score 3.85(0)(P<0.001).There was no skin pigmentation,pain in the injection area,local urticaria and blistering after sclerotherapy,no adverse reactions such as cyst bleeding and drunkenness-like reaction,and no serious complications occurred.There were 2 cases of cysts that presented infection with fever,and no serious complications occurred.Conclusions Ultrasound-guided percutaneous sclerotherapy is a safe and effective minimally invasive treatment for thyroglossal duct cysts in children.
作者
张潇
蔡文佳
王生才
万佳彬
丁娇娇
刘原虎
倪鑫
石文媛
Zhang Xiao;Cai Wenjia;Wang Shengcai;Wan Jiabin;Ding Jiaojiao;Liu Yuanhu;Ni Xin;Shi Wenyuan(Department of Ultrasound,Beijing Children′s Hospital,Capital Medical University,National Children′s Medical Center,Beijing 100045,China;Department of Otolaryngology and Head and Neck Surgery,Beijing Children′s Hospital,Capital Medical University,National Children′s Medical Center,Beijing 100045,China)
出处
《中华超声影像学杂志》
CSCD
北大核心
2023年第4期348-353,共6页
Chinese Journal of Ultrasonography
基金
吴阶平医学基金会临床科研专项资助基金(320.6750.2022-03-21)。
关键词
超声检查
甲状舌管囊肿
儿童
硬化治疗
Ultrasonography
Thyroglossal duct cysts
Children
Sclerotherapy