摘要
目的探讨循经刮痧治疗化疗所致白细胞减少症的临床效果及安全性。方法回顾性分析2022年2月—2022年12月日照市中医医院收治的50例化疗所致白细胞减少症患者临床资料,将接受重组人粒细胞刺激因子治疗的25例患者设为对照组,将接受重组人粒细胞刺激因子联合循经刮痧治疗的25例患者设为观察组。比较两组患者的白细胞分度、血常规指标、免疫功能、肝肾功能及不良反应。结果观察组患者治疗后白细胞分度低于对照组,差异有统计学意义(P<0.05);观察组患者治疗后白细胞计数(WBC)、中性粒细胞计数(NE)、血红蛋白(HGB)、红细胞计数(RBC)高于对照组,差异有统计学意义(P<0.05);观察组患者治疗后CD3^(+)、CD4^(+)水平及CD4^(+)/CD8^(+)高于对照组,CD8^(+)水平低于对照组,差异有统计学意义(P<0.05);两组患者治疗前后肝肾功能比较,差异无统计学意义(P>0.05);两组不良反应发生率比较,差异无统计学意义(P>0.05)。结论循经刮痧治疗可提高化疗所致白细胞减少症治疗效果,加快WBC、NE等恢复正常水平,改善白细胞分度,增强机体免疫功能,且对肝肾功能无明显影响,安全可靠。
Objective To investigate the clinical effect and safety of scraping and scraping along the meridian in the treatment of chemotherapy-induced leukopenia.Methods The clinical data of 50 patients with leukopenia caused by chemotherapy admitted to Rizhao traditional Chinese medicine hospital from February 2022 to December 2022 were retrospectively analyzed.25 patients who received recombinant human granulocyte stimulating factor treatment were set as the control group,and 25 patients who received recombinant human granulocyte stimulating factor combined with Meridian Scraping Therapy were set as the observation group.White blood cell division,blood routine index,immune function,liver and kidney function and adverse reactions were compared between the two groups.Results After treatment,the leukocyte division of the observation group was lower than that of the control group(P<0.05);the white blood cell count(WBC),neutrophil count(NE),hemoglobin(Hgb)and red blood cell count(RBC)in the observation group were higher than those in the control group after treatment,and the difference was statistically significant(P<0.05);after treatment,the level of CD3^(+),CD4^(+)and CD4^(+)/CD8^(+)in the observation group was higher than that in the control group,and the level of CD8^(+)was lower than that in the control group(P<0.05);there was no significant difference in liver and kidney function between the two groups before and after treatment(P>0.05);there was no significant difference in adverse reactions between the two groups(P>0.05).Conclusion Scraping along the meridian can improve the therapeutic effect of chemotherapy-induced leukopenia,accelerate the normalization of WBC and NE,improve leukocyte differentiation,and enhance the immune function of the body.It has no obvious effect on liver and kidney functions,and is safe and reliable.
作者
徐艳
闫君梅
李晓芳
XU Yan;YAN Jun-mei;LI Xiao-fang(Department of Oncology,Rizhao Hospital Of TCM,Rizhao Shandong 276800,China)
出处
《中华养生保健》
2023年第11期21-25,共5页
CHINESE HEALTH CARE
关键词
化疗
白细胞减少症
循经刮痧
生活质量
chemotherapy
leukopenia
scraping along the meridian
quality of life
