摘要
认知障碍是放射性脑损伤最常见的临床表现,主要依据临床表现与神经心理学量表诊断,临床上尚无法做到早期诊断。放疗后认知障碍的发展与放射性脑损伤的病理过程相关。本文综述了放疗后认知障碍相关的病理过程与MRI在放疗后认知障碍应用的最新进展,总结了不同序列放射性脑损伤的早期影像学表现和相对应的病理改变,以及基于MRI的人工智能和影像组学在预测放疗后认知障碍患者的应用,并基于此提出人工智能和影像组学结合多序列MRI早期诊断放疗后认知障碍的研究方向,有助于临床早期准确识别放疗后认知障碍患者并尽早干预,提升患者生活质量。
Cognitive function impairment is the most common clinical manifestation of radiation-induced brain injury.The diagnosis is mainly based on clinical features and neuropsychological scales.The process of cognitive function impairment after radiotherapy is related to the pathological changes.This article reviews the latest progress in the pathological processes related to cognitive function impairment after radiotherapy and the application of MRI.It summarizes the early imaging manifestations and corresponding pathological changes of radiation-induced brain injury in different sequences,and the application of artificial intelligence and radiomics based on MRI in predicting patients with cognitive function impairment after radiotherapy.Based on this,the research direction of artificial intelligence and radiomics combined with multi-sequence MRI for early diagnosis of cognitive function impairment after radiotherapy is proposed,which is helpful for early and accurate identification of patients with cognitive function impairment after radiotherapy and early intervention to improve the quality of life of patients.
作者
张丹妮
邹悄悄
王铭梁
李文彬
ZHANG Danni;ZOU Qiaoqiao;WANG Mingliang;LI Wenbin(Department of Radiology,Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine,Shanghai 200030,China)
出处
《磁共振成像》
CAS
CSCD
北大核心
2023年第5期155-160,共6页
Chinese Journal of Magnetic Resonance Imaging
基金
国家自然科学基金(编号:81901727)。
关键词
放射性脑损伤
病理改变
认知障碍
磁共振成像
radiation-induced brain injury
pathological changes
cognitive impairment
magnetic resonance imaging
