摘要
目的 研究左炔诺孕酮宫内缓释系统与口服避孕药对子宫内膜息肉患者术后的效果。方法 方便选择2020年4月—2021年4月徐州市妇幼保健院门诊收治的110例子宫内膜息肉患者作为研究对象,所有患者均行宫腔镜手术,应用随机数表法将其分成两组,各55例。对照组术后口服短期避孕药,观察组术后放置左炔诺孕酮宫内缓释系统进行治疗。对比两组患者术后3、6、12个月子宫内膜厚度以及复发率、血红蛋白水平及月经情况。结果 治疗后3、6、12个月,观察组子宫内膜厚度、月经失血图评分均低于对照组,血红蛋白水平高于对照组,差异有统计学意义(P<0.05);治疗后12个月,观察组无复发,对照组复发率10.91%(6/55),差异有统计学意义(χ^(2)=4.407,P=0.036)。结论 左炔诺孕酮宫内缓释系统用于子宫内膜息肉患者术后可降低子宫内膜厚度,预防子宫内膜增生,可以降低复发率,能够有效改善血红蛋白水平和月经情况,促进患者术后恢复。
Objective To study the effect of levonorgestrel intrauterine sustained-release system and oral contraceptives on postoperative patients with endometrial polyps.Methods 110 patients with endometrial polyps admitted to the outpatient department of Xuzhou Maternal and Child Health Hospital from April 2020 to April 2021 were conveniently selected as the research subjects.All patients underwent hysteroscopic surgery and were divided into two groups using random number table method,with 55 patients in each group.The control group received short-term oral contraceptives after surgery,while the observation group received treatment with a levonorgestrel intrauterine sustained-release system after surgery.Compared the endometrial thickness,recurrence rate,hemoglobin levels,and menstrual status of two groups of patients at 3,6,and 12 months after surgery.Results At 3 months,6 months,and 12 months after treatment,the endometrial thickness,menstrual bleeding map score of the observation group were lower than those of the control group,and the hemoglobin levels was higher than that of the control group,and the difference was statistically significant(P<0.05);after 12 months of treatment,there was no recurrence in the observation group,while the recurrence rate in the control group was 10.91%(6/55),and the difference was statistically significant(χ^(2)=4.407,P=0.036).Conclusion Levonorgestrel intrauterine sustained-release system can reduce endometrial thickness and prevent endometrial hyperplasia in patients with endometrial polyps,can reduce the recurrence rate,can effectively improve the hemoglobin level,improve menstrual conditions,and promote postoperative recovery of patients,and is worthy of popularization and application.
作者
王海燕
WANG Haiyan(Department of Obstetrics and Gynecology,Xuzhou Maternal and Child Health Hospital,Xuzhou,Jiangsu Province,221000 China)
出处
《中外医疗》
2023年第5期142-145,150,共5页
China & Foreign Medical Treatment
关键词
左炔诺孕酮宫内缓释系统
避孕药
子宫内膜息肉
复发率
血红蛋白
Levonorgestrel intrauterine sustained-release system
Contraceptives
Endometrial polyps
Recurrence rate
Hemoglobin
