摘要
和厚朴酚作为中药厚朴(Magnoliae Officinalis Cortex)的主要活性成分之一,具有广泛的药理作用,除了抗菌、抗炎、抗氧化等作用外,对神经胶质瘤、鼻咽癌、舌癌、喉癌等肿瘤亦有较好的药理活性。本文主要围绕和厚朴酚对神经胶质瘤和鼻咽癌、舌癌、喉癌等头颈部肿瘤的药理作用及其机制进行了综述,并对相关研究进行了分析。
Honokiol,as one of main active ingredients of the traditional Chinese medicine Magnoliae Officinalis Cortex,has a wide range of pharmacological effects.In addition to antibacterial,anti-inflammatory,and anti-oxidative effects,it also has good pharmacological activity against glioma,nasopharyngeal carcinoma,tongue cancer,laryngeal cancer,etc.In this article,the pharmacological effects and mechanism of honokiol on glioma,nasopharyngeal carcinoma,tongue cancer,laryngeal cancer and other head-neck tumors are reviewed,and the related researches are analyzed.
作者
张明发
沈雅琴
ZHANG Ming-fa;SHEN Ya-qin(Shanghai Meiyou Pharmaceutical Co.,Ltd.,Shanghai 201204,China)
出处
《抗感染药学》
2023年第1期1-5,共5页
Anti-infection Pharmacy
关键词
和厚朴酚
经胶质瘤
鼻咽癌
舌癌
喉癌
药理作用
作用机制
honokiol
glioma
nasopharyngeal carcinoma
tongue cancer
laryngeal cancer
pharmacological effect
mechanism of action
