期刊文献+

一氧化氮合酶抑制剂L-NAME抗大鼠血管平滑肌细胞增殖的作用 被引量:1

Antiproliferative effect of nitric oxide synthase inhibitor L-NAME on rat vascular smooth muscle cells
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摘要 许多血管性疾病的产生与一氧化氮(NO)生成不足有关,如:高血压、动脉硬化、PTCA术后再狭窄及与感染性休克相关的血管反应性降低等.NO是由细胞内的左旋精氨酸(L-arginine,L-Arg)经一氧化氮合酶(nitric oxide synthase,NOS)作用而生成的.NO的合成可以被酶抑制剂NG-硝基-L-精氨酸甲酯(L-NG-nitro-arginine methyl ester,L-NAME)、氨基胍(aminoguanidine)等抑制.
出处 《第二军医大学学报》 CAS CSCD 北大核心 2002年第11期1271-1272,共2页 Academic Journal of Second Military Medical University
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