摘要
动物接种疫苗后免疫抗体效价是评价免疫效果的一项重要指标,是衡量一个区域内群体免疫屏障稳固与否的最重要的依据,提高免疫抗体效价可以有效控制疫病发生、流行,保障畜牧业的健康发展。近几年来,我市在重大动物强制免疫效果评价工作中,藏系羊口蹄疫免疫抗体疫效价整体不高,2019-2021年兽医实验室采用液相阻断ELISA试验检测羊血清样品2 541份、2 786份、2 980份,但每批次检测的血清样品整体的免疫抗体合格率在55%~75%之间,这与上级部门要求的免疫抗体合格率常年保持在70%以上的标准有一定的差距。本文就藏系羊口蹄疫疫苗免疫抗体效价不高产生的原因进行分析,并提出应对措施,旨在解决我市藏系羊口蹄疫防控中免疫抗体疫效价整体不高的问题,建立起有效的免疫屏障,保障我市羊产业的高质量发展。
The immune antibody titer after animal vaccination is an important index to evaluate the immune effect.This is the most important basis for measuring the stability of the herd immunity barrier in a region.This can effectively control the occurrence and prevalence of epidemic diseases by improving the titer of immune antibodies,and ensure the healthy development of animal husbandry.In recent years,in the evaluation of the effect of major animal compulsory immunization in our city,the anti-antibody titer of Tibetan sheep FMD immunity is not high as a whole.From 2019 to 2021,2,541,2,786,and 2,980 sheep serum samples were tested by liquid-phase blocking ELISA in veterinary laboratories,but the overall immune antibody pass rate of each batch of serum samples tested was between 55%and 75%.There is a certain gap between this and the requirement of higher authorities that the pass rate of immune antibodies should be kept above 70%all the year round.This paper analyzes the reasons for the low antibody titer of Tibetan sheep foot-and-mouth disease vaccine and puts forward countermeasures.This aims to solve the problem of the overall low titer of immune antibodies in the prevention and control of foot-and-mouth disease in Tibetan sheep in our city,establish an effective immune barrier,and ensure the high-quality development of the sheep industry in our city.
作者
朱晓文
ZHU Xiao-wen(Linxia Animal Disease Prevention and Control Center,Linxia,Gansu 731100,China)
出处
《畜牧兽医杂志》
2023年第3期123-125,共3页
Journal of Animal Science and Veterinary Medicine
关键词
藏系羊
口蹄疫疫苗
免疫
抗体效价
措施
Tibetan sheep
foot-and-mouth disease vaccine
immunity
antibody titer
measures
