摘要
代谢综合征(MS)是一组以肥胖、高血糖(糖尿病或糖调节受损)、血脂异常即高三酰甘油血症和(或)低高密度脂蛋白胆固醇血症,以及高血压等聚集发病,严重影响机体健康的临床征候;由于存在多种物质代谢异常,促发动脉粥样硬化等多种危险因素的聚集,最终容易引起各种心脑血管疾病的发生和发展。倪青教授认为代谢综合征患者由于饮食不节致胃肠运化功能受损,内生痰湿瘀毒,壅滞于胃肠、三焦之腑,以致六腑功能失调。六腑受损是伴有肥胖的代谢综合征患者的首要病机,其病程演变基本可归纳为六腑腑气损伤为先,继而腑病及脏,最终脏腑同病。这与现代医学研究代谢综合征与肠道菌群失调及脑-肠-微生物失平衡不谋而合。倪教授认为本病存在多种人体代谢指标的异常,治疗应发挥中医优势,具有整体观念,病症结合,综合分析各代谢指标异常的相关性,权衡利弊,合理选方用药,临床治疗本病,善于从“腑”论治,提倡应用合方。
Metabolic syndrome(MS)is a clinical condition characterized by a cluster of pathologies,including obesity,high blood glucose(diabetes or impaired glucose tolerance),dyslipidemia(elevated triglycerides and/or reduced high-density lipoprotein cholesterol),and hypertension,which seriously affects the body health.These abnormalities in metabolism can lead to the development of various cardiovascular and cerebrovascular diseases due to the aggregation of multiple risk factors such as atherosclerosis.Professor Ni Qing believes that MS patients may suffer from impaired gastrointestinal function due to poor dietary habits,leading to the accumulation of endogenous phlegm-dampness and blood stasis,which stagnates in the stomach,intestine,and triple energizer,causing dysfunction of the six Fu organs.Damage to the six Fu organs is the primary pathology in obese patients with MS,whose disease progression can be summarized as initial impairment of viscera qi,followed by organ and viscera diseases,and ultimately the development of systemic disease.This is consistent with modern medical research on the imbalance of gut microbiota and brain-gut-microbiota axis in MS patients.Professor Ni believes that since MS involves multiple abnormalities in human metabolic indicators,treatment should leverage the advantages of traditional Chinese medicine(TCM),taking into account the overall concept,combining disease and syndrome,analyzing the relevance of various abnormal metabolic indicators,weighing the pros and cons,and using appropriate drugs and prescriptions in clinical practice,with emphasis on the treatment of the six Fu organs and advocating the use of combined prescriptions.
作者
汪燕燕
张美珍
贺璞玉
倪青
WANG Yanyan;ZHANG Meizhen;HE Puyu;NI Qing(Department of Endocrinology,Yinchuan Traditional Chinese Medicine Hospital Affiliated to Ningxia Medical University,Ningxia 750001,China;Department of Endocrinology,Guang′anmen Hospital,China Academy of Chinese Medical Sciences,Beijing 100053,China)
出处
《世界中医药》
CAS
2023年第10期1437-1441,共5页
World Chinese Medicine
基金
宁夏重点研发计划项目(2021BEG03106)
宁夏自治区第七批优秀中医临床人才研修项目(宁卫计中医[2019]5号)
宁夏青年人才托举工程项目(TJGC2017053)
京宁合作中医重点专科建设项目(2018DPG05014)
银川市科技计划项目(2021-SF-002)。
关键词
肥胖
2型糖尿病
代谢综合征
病证结合
从腑论治
名中医经验
@倪青
Obesity
Type 2 diabetes
Metabolic syndrome
Combination of disease and syndrome
Treatment from Fu organs
Experience of famous TCM doctor
@Ni Qing
