摘要
目的探讨全身骨显像与SPECT/CT在人类免疫缺陷病毒阴性非结核分枝杆菌感染骨破坏的影像学特点及诊断价值。方法回顾性分析2020年11月~2022年7月在我院行全身骨显像及SPECT/CT显像并且确诊为非结核分枝杆菌(NTM)感染的25例患者,总结NTM感染骨破坏的临床表现、影像学表现等,并比较两种显像方法的诊断效能。结果全身骨显像诊断NTM感染骨破坏的敏感度为94.7%,特异性为100%,诊断符合率为96%;SPECT/CT显像诊断NTM感染骨破坏的敏感度、特异性、诊断符合率均为100%;二者对NTM感染骨破坏的诊断符合率的差异有统计学意义(P<0.05)。病变主要分布于肋骨、四肢长骨、脊柱等部位,在全身骨显像上表现为放射性浓聚影,SPECT/CT可见以溶骨性改变为主。结论全身骨显像联合SPECT/CT断层融合显像可以监测到全身多个部位的病变,较好地显示NTM感染骨破坏的代谢情况及影像学特征,为临床诊疗提供帮助。
Objective To investigate the imaging characteristics and diagnostic value of whole-body bone scan and SPECT/CT in nontuberculous mycobacterial-infected bone destruction in HIV-negative patients.MethodsWe retrospectively analyzed 25 patients with nontuberculous mycobacterial(NTM)who underwent whole-body bone scan and SPECT/CT in our hospital from November 2020 to July 2022.The clinical and imaging characteristics of NTM-infected bone destruction were summarized,and the diagnostic efficacy of the two imaging methods was compared.Results The sensitivity of the wholebody bone scan for the diagnosis of NTM-infected bone destruction was 94.7%,the specificity was 100%,and the diagnostic coincidence rate was 96%.The sensitivity,specificity,and diagnostic compliance rate of SPECT/CT were 100%.There was a significant difference in the diagnostic compliance rate of the two methods in diagnosing NTM-infected bone destruction(P<0.05).The lesions were mainly distributed in the ribs,long bone of extremities,and spinal column,manifested as intense radioactive uptake on whole-body bone scan,and mostly showed osteolytic changes on SPECT/CT.Conclusion Whole-body bone scan combined with SPECT/CT imaging can monitor lesions in multiple parts of the body and better show the metabolic situation and imaging characteristics of NTM-infected bone destruction,which can help clinical diagnosis and treatment.
作者
梁翔玥
罗安强
赵跃群
李俊红
韦智晓
LIANG Xiangyue;LUO Anqiang;ZHAO Yuequn;LI Junhong;WEI Zhixiao(Department of Nuclear Medicine,The First Affiliated Hospital of Guangxi Medical University,Nanning 530021,China)
出处
《分子影像学杂志》
2023年第3期458-463,共6页
Journal of Molecular Imaging
基金
广西自然科学基金面上项目(2017GXNSFAA198287)
广西卫健委适宜技术项目(S2018077)。
