摘要
目的研究阴道超声、腹部超声与β人绒毛膜促性腺激素(β-HCG)、孕酮在诊断宫外孕中的价值。方法开展回顾性分析,将医院妇产科2019年1月~2022年10月收治的63例宫外孕患者纳为宫外孕组,同期60例妊娠时间相似的正常孕早期妇女作为对照组。比较两组阴道超声及腹部超声检查资料及β-HCG、孕酮水平,分析阴道超声、腹部超声、β-HCG及孕酮水平在诊断宫外孕中的价值。结果宫外孕组患者外周血β-HCG、孕酮水平及子宫内膜厚度均低于对照组,差异有统计学意义(P<0.05)。阴道超声附件区包块检出率高于腹部超声,差异有统计学意义(P<0.05),两组胎芽、胎心搏动、盆腔积液、同侧卵巢显示及对侧卵巢显示率比较,差异无统计学意义(P>0.05)。β-HCG、孕酮及子宫内膜厚度单独应用时在诊断宫外孕中的效能分别为AUC=0.732,95%CI:0.642~0.823;AUC=0.719,95%CI:0.626~0.812;AUC=0.803,95%CI:0.720~0.885,三指标联合应用在诊断宫外孕中的价值最高(AUC=0.862,95%CI:0.790~0.934)。结论阴道超声、经腹超声及β-HCG、孕酮联合应用可有效提高宫外孕诊断效果。
Objective To evaluate the clinical value of transvaginal and abdominal ultrasound combined with serumβ-human chorionic gonadotropin(β-HCG)and progesterone detection in the diagnosis of ectopic pregnancy.Methods A retrospective analysis was performed.Sixty-three patients with ectopic pregnancy admitted to obstetrics and gynecology department of our hospital from January 2019 to October 2022 were included in ectopic pregnancy group,and 60 normal early pregnant women with similar gestational weeks were enrolled as control group.The data including transvaginal and abdominal ultrasound results,and serum levels ofβ-HCG and progesterone were compared between two groups.Then the value of transvaginal ultrasound,abdominal ultrasound,β-HCG and progesterone levels in the diagnosis of ectopic pregnancy were evaluated.Results Compared with control group,ectopic pregnancy group had lower levels ofβ-HCG and progesterone in peripheral blood and thinner endometrial thickness,with statistical difference(P<0.05).The detection rate of pelvic adnexal mass of transvaginal ultrasound was higher than that of abdominal ultrasound(P<0.05),while no statistical difference was found in the detection rates of embryo bud,fetal heart beat,pelvic effusion,and the display in both ipsilateral and contralateral ovarian(P>0.05).The efficacy ofβ-HCG,progesterone and endometrial thickness alone in the diagnosis of ectopic pregnancy was as follow:AUC=0.732,95%CI:0.642-0.823;AUC=0.719,95%CI:0.626-0.812;AUC=0.803,95%CI:0.720-0.885,and the combined detection of three indexes in diagnosis of ectopic pregnancy had the highest value than that of separate detection(AUC=0.862,95%CI:0.790-0.934).Conclusion The combined application of transvaginal and abdominal ultrasound combined with serumβ-HCG and progesterone detection can effectively improve the diagnostic efficacy of ectopic pregnancy.
作者
杨姝娇
田亚娜
余影
YANG Shujiao;TIAN Yana;YU Ying(Department of Ultrasound,Fuyang Women and Children's Hospital,Fuyang 236000,China)
出处
《分子影像学杂志》
2023年第3期513-517,共5页
Journal of Molecular Imaging
基金
阜阳市卫健委科研项目(2022-02)。
关键词
宫外孕
诊断
阴道超声
腹部超声
Β人绒毛膜促性腺激素
孕酮
ectopic pregnancy
diagnosis
transvaginal ultrasound
abdominal ultrasound
β-human chorionic gonadotropin
progesterone
