摘要
目的:基于郑玉玲教授治疗甲状腺癌的门诊病例资料,采用数据挖掘方法,探析并总结其用药组方规律。方法:通过肿瘤临床诊疗与患者管理一体化平台软件导出就诊于郑玉玲教授门诊的患者资料,对其病历信息、中药处方进行频数统计、聚类分析、因子分析、关联规则分析等,挖掘其中的用药规律和组方特点。结果:符合纳入条件的患者61例,纳入处方168首,高频方剂为当归芍药散、软坚消积汤、逍遥散、越鞠丸和薯蓣丸,将高频药物进行数据分析后,得到3类药物组合、11组常用药对。核心药物以性温为主,平为次,味辛为主、苦为次;归脾经居多,肺经、肝经次之;药物种类以补虚药为主,清热药及活血化瘀药次之,各占12.55%、9.04%、6.20%。结论:郑玉玲教授认为甲状腺癌与气滞、痰凝和血瘀有关,治疗以行气活血,化痰散结,补益气血为主。
Objective:Based on the outpatient case data of Professor Zheng Yuling in the treatment of thyroid cancer,using data mining methods,to explore and summarize the medication rules of her prescriptions.Methods:The data of patients who visited Professor Zheng Yuling′s outpatient clinic were exported through the integrated platform software of tumor clinical diagnosis and treatment and patient management,and the frequency statistics,cluster analysis,factor analysis,association rule analysis,etc.were carried out on the medical record information and TCM prescriptions,and the medication rules and prescription characteristics were excavated.Results:61 patients met the inclusion criteria,and 168 prescriptions were included.The high-frequency prescriptions were Danggui Shaoyao Powder,Ruanjian Xiaoji Decoction,Xiaoyao Powder,Yueju Pills,and Shuying Pills.After the data analysis of high-frequency drugs,three types of drug combinations and 11 commonly used drug pairs were obtained.The core drugs are mainly warm in nature,followed by flatness,pungent in taste,followed by bitterness.Most of them are belonged to the Spleen meridian,followed by the Lung meridian and Liver meridian.The types of drugs are mainly tonic drugs,followed by heat-clearing drugs and Blood-activating and stasis-removing drugs,accounting for 12.55%,9.04%,and 6.20%respectively.Conclusion:Professor Zheng Yuling believes that thyroid cancer is related to Qi stagnation,phlegm coagulation,and Blood stasis.And her treatment is mainly based on promoting Qi and Blood circulation,resolving phlegm and dispelling stagnation,and replenishing Qi and Blood.
作者
刘梦雅
郑玉玲
张亚玲
朱燃培
LIU Mengya;ZHENG Yuling;ZHANG Yaling;ZHU Ranpei(Henan University of Chinese Medicine,Zhengzhou Henan China 450046;The First Affiliated Hospital of Henan University of Chinese Medicine,Zhengzhou Henan China 450000)
出处
《中医学报》
CAS
2023年第6期1256-1262,共7页
Acta Chinese Medicine
基金
全国名老中医药专家传承工作室建设项目{国中医药人教函[2022]75号}
全国名中医传承工作室建设项目{国中医药办人教函[2022]245号}。
关键词
甲状腺癌
用药规律
郑玉玲
数据挖掘
thyroid cancer
medication rule
Zheng Yuling
data mining
