摘要
急性缺血性脑卒中是最为常见的缺血性脑血管疾病之一,该病在超早期治疗的首选方法是静脉溶栓。超高龄患者采用静脉溶栓可能会从一定程度上增加颅内出血性转化的风险,影响治疗的安全性与有效性,国内外尚缺乏基于循证医学证据的有力推荐。本文报道1例97岁超高龄急性缺血性脑卒中患者接受静脉溶栓治疗的成功案例,并对相关文献进行回顾分析。该病例提示临床上对急性缺血性脑卒中患者需要进行综合评估,权衡利弊后合理选择治疗方案,在保证临床获益的同时尽量降低颅内出血性转化发生率。
Acute ischemic stroke is one of the most common ischemic cerebrovascular diseases,and the preferred method of treatment for this disease in its super early stage is intravenous thrombolysis.As the use of intravenous thrombolysis in the oldest-old patients may increase the risk of intracranial hemorrhagic transformation to some extent and compromise the safety and efficacy of treatment,there is a lack of medical evidence-based and firm recommendations for it,both domestically and internationally.This article reports a successful case of a 97-year-old patient with acute ischemic stroke who received intravenous thrombolytic therapy,and reviews the relevant literature.This case suggests the need for a comprehensive clinical assessment of patients with acute ischemic stroke and a rational choice of treatment options after weighing the advantages and disadvantages to ensure clinical benefit while minimizing the incidence of intracranial hemorrhagic transformation.
作者
赵见文
王传尊
闫瑞萍
杨京花
ZHAO Jianwen;WANG Chuanzun;YAN Ruiping;YANG Jinghua(Department of Encephalopathy,Cangzhou Hospital of Integrated Chinese and Western Medicine,Hebei,Cangzhou 061001,China)
出处
《中国医药科学》
2023年第10期187-190,共4页
China Medicine And Pharmacy
基金
河北省“三三三人才工程”资助项目(沧人社字[2020]64号)
河北省中医药管理局科研计划项目(2020516)。
关键词
急性缺血性脑卒中
临床报道
文献回顾
颅内出血性转化
Acute ischemic stroke
Clinical reports
Literature review
Intracranial hemorrhagic transformation
