摘要
在Na_(2)HPO_(4)·12H_(2)O催化剂作用下,通过Carroll反应,以芳樟醇与乙酰乙酸乙酯为原料合成了香叶基丙酮。考察反应温度、反应时间、物料摩尔比、催化剂用量对香叶基丙酮产率的影响。结果表明,优化出香叶基丙酮合成工艺为:反应温度174℃,反应时间7 h,芳樟醇与乙酰乙酸乙酯摩尔比1∶2.0,催化剂用量为3%(以芳樟醇质量为基准)。优化工艺条件下,香叶基丙酮的产率达89.1%。
Through the Carroll reaction,geranylacetone was synthesized from linalool and ethyl acetoacetate catalyzed by Na_(2)HPO_(4)·12H_(2)O.The influence of reaction temperature,reaction time,molar ratio of material,catalyst dosage on geranylacetone yield were investigated.The result showed that the optimized synthesis process conditions were obtained as follows:reaction temperature 174℃,reaction time 7 h,molar ratio of linalool to ethyl acetoacetate 1∶2.0,and catalyst dosage 3%(based on the mass of linaloo).The practical yield of geranylacetone reaches 89.1%under the optimized conditions mentioned above.
作者
文宽
杨国恩
阳宏祥
霍赫
杨祥宇
WEN Kuan;YANG Guo-en;YANG Hong-xiang;HUO He;YANG Xiang-yu(College of Material Science and Engineering,Central South University of Forestry and Technology,Changsha 410004,China)
出处
《应用化工》
CAS
CSCD
北大核心
2023年第5期1414-1419,共6页
Applied Chemical Industry
基金
湖南省科技计划重点研发计划项目(2015NK3023)。
关键词
芳樟醇
香叶基丙酮
合成
磷酸氢二钠
linalool
geranylacetone
synthesis
disodium phosphate
