摘要
目的分析琥珀酸亚铁片加维生素C对妊娠期缺铁性贫血(IDA)的疗效。方法选取2019年1月—2021年8月进贤县妇幼保健院收治的妊娠期IDA患者66例为研究对象,依据随机数字表法分成对照组(除常规治疗外加以琥珀酸亚铁片)和观察组(在对照组基础上加以维生素C)各33例,对比2组治疗有效率,治疗前后血清铁(SI)、转铁蛋白饱和度(TSAT)、血红蛋白(Hb)、红细胞(RBC)、红细胞血红蛋白平均浓度(MCHC)、红细胞平均体积(MCV),外周血CD_(4)^(+)、CD_(8)^(+)、CD_(4)^(+)/CD_(8)^(+)、CD_(3)^(+)水平及副反应出现情况。结果观察组有效率高于对照组(P<0.05)。治疗前,2组Hb、RBC、MCHC、MCV、SI、TSAT、CD_(4)^(+)、CD_(3)^(+)、CD_(8)^(+)及CD_(4)^(+)/CD_(8)^(+)水平对比无显著差异(P>0.05);治疗后,观察组Hb、RBC、MCHC、MCV、SI、TSAT、CD_(4)^(+)、CD_(3)^(+)及CD_(4)^(+)/CD_(8)^(+)水平均高于对照组,CD_(8)^(+)水平低于对照组(P<0.05)。2组恶心呕吐、皮疹、便秘以及腹痛等副反应发生率相比无明显差异(P>0.05)。结论琥珀酸亚铁片加维生素C对妊娠期IDA疗效确切,能改善患者的血常规与铁代谢指标,提升机体免疫力,同时不会显著增加副反应,安全性较高。
Objective To analyze the effectiveness of ferrous succinate tablets plus vitamin C in treating iron deficiency anemia(IDA).Methods 66 pregnant women with IDA treated from January 2019 to August 2021 in our hospital were chosen as research subjects.According to random number table,women were divided into control group(33 cases)and observation group(33 cases).The control group took the routine treatment and ferrous succinate tablets;on the basis of the former,the observation group took vitamin C.Group contrast results were appraised through the effective rate,serum iron(SI),transferrin saturation(TSAT),hemoglobin(Hb),red blood cell(RBC),mean corpuscular hemoglobin concentration(MCHC),mean corpuscular volume(MCV),peripheral blood CD_(4)^(+),CD_(8)^(+),CD_(4)^(+)/CD_(8)^(+)and CD_(3)^(+)and adverse reactions.Results The effective rate in the observation group was higher than control group(P<0.05);before therapy,Hb,RBC,MCHC,MCV,SI,TSAT,CD_(4)^(+),CD_(3)^(+),CD_(8)^(+)and CD_(4)^(+)/CD_(8)^(+)levels between groups were not significantly different.After therapy,Hb,RBC,MCHC,MCV,SI,TSAT,CD_(4)^(+),CD_(3)^(+)and CD_(4)^(+)/CD_(8)^(+)levels in the observation group were higher than control group,but CD_(8)^(+)levels were lower than control group(P<0.05);the incidences of adverse reactions like nausea,vomiting,skin rash,constipation and abdominal pain between groups were not significantly different(P>0.05).Conclusion The ferrous succinate tablets and vitamin C has obvious effects for the treatment of IDA,which can produce less impact on the adverse reactions,and improve the blood routine examination and iron metabolism indicators,immune function and treatment safety.
作者
杨凤仙
Yang Fengxian(The Maternity and Child Health Hospital of Jinxian County,Jinxian,Jiangxi 331700)
出处
《基层医学论坛》
2023年第17期7-10,共4页
The Medical Forum
关键词
缺铁性贫血
妊娠期
维生素C
琥珀酸亚铁片
铁代谢
免疫功能
副反应
Iron deficiency anemia
Pregnancy
Vitamin C
Ferrous succinate tablets
Iron metabolism
Immune function
Adverse reactions
