摘要
碘对比剂是临床不可缺少的X射线阳性显像剂,在临床影像学诊断中发挥重要作用。碘对比剂相关性急性肾损伤(PC-AKI)是该药使用过程中严重并发症之一,虽然大多数肾功能损伤是暂时的,但也有少部分患者出现严重的后果,如慢性肾脏病、肾功能不全等,严重者可能需要肾移植甚或导致死亡。因此,寻找有效的方法早期识别、及时规避PC-AKI的发生有重要的临床意义。本文就PC-AKI的发病机制、危险因素、早期诊断及防治方法进行综述,旨在提高对该病的认识。
Iodine contrast agents are indispensable X-ray-positive imaging agents in clinical practice, and play an important role in clinical imaging diagnosis. Iodine contrast agent-associated acute kidney injury(PC-AKI) is one of the serious complications during the use of this drug. Although most renal function damage is temporary, there are also a few patients who have serious consequences, such as chronic kidney disease, renal insufficiency, and severe cases that may require kidney transplantation or even lead to death. Therefore, finding effective methods to early identify and timely avoid the occurrence of PC-AKI have important clinical significance. This article reviews the pathogenesis, risk factors, early diagnosis, and prevention and treatment of PC-AKI in order to improve understanding of the disease.
作者
王联芙
洪奇
李强
WANG Lianfu;HONG Qi;LI Qiang(Department of Imaging,Peoples Hospital Affiliated to Ningbo University,Ningbo 315040,China)
出处
《医学影像学杂志》
2023年第5期889-892,共4页
Journal of Medical Imaging
基金
浙江省自然科学基金基础公益研究计划项目(编号:LGF20H180005)
浙江省医药卫生青年人才计划项目(编号:2019RC273)。
