摘要
目的:分析进展性脑梗死患者的危险因素,总结临床治疗方法及效果。方法:选取2021年1月—2022年7月四川省攀枝花市第二人民医院神经科收治的脑梗死患者112例作为研究对象,根据疾病诊断不同分为进展性脑梗死组(n=44)和常规脑梗死组(n=68)。比较两组患者临床资料,分析危险因素。进展性脑梗死组给予奥扎格雷钠、巴曲酶治疗,常规脑梗死组实施常规治疗,通过美国国立卫生研究院卒中量表(NIHSS)评分分析其临床疗效。结果:同型半胱氨酸、颈动脉狭窄>50%、纤维蛋白原、血糖、总胆固醇、甘油三酯是进展性脑梗死患者的主要危险因素,差异有统计学意义(P<0.05)。治疗后,进展性脑梗死患者的治疗总有效率为90.91%;治疗后3、7、21d患者NIHSS评分均高于治疗前,差异有统计学意义(F=8.414,P=0.001)。结论:进展性脑梗死的危险因素较多,应重视对患者情况的全面了解,评估治疗风险性,可给予奥扎格雷钠、巴曲酶治疗。
Objective:To analyze the risk factors of patients with progressive cerebral infarction,and to summarize the clinical treatment methods and effects.Methods:From January 2021 to July 2022,one hundred and twelve patients with cerebral infarction admitted to the Department of Neurology,Panzhihua Second People's Hospital,Sichuan Province were selected as the research objects.According to different disease diagnoses,they were divided into progressive cerebral infarction group(n=44)and conventional cerebral infarction group(n=68).The clinical data of the two groups were compared and the risk factors were analyzed.The progressive cerebral infarction group was treated with sodium ozagrel and batroxobin,and the conventional cerebral infarction group was given conventional treatment.The clinical efficacy was analyzed by the National Institutes of Health Stroke Scale(NIHSS)score.Results:Homocysteine,carotid artery stenosis>50%,fibrinogen,blood sugar,total cholesterol,triglyceride were the main risk factors in patients with progressive cerebral infarction,and the difference was statistically significant(P<0.05).After treatment,the total effective rate of patients with progressive cerebral infarction was 90.91%;3,7,and 21 days after treatment,the NIHSS scores of patients were higher than those before treatment,and the difference was statistically significant(F=8.414,P=0.001).Conclusion:There are many risk factors for progressive cerebral infarction,and attention should be paid to a comprehensive understanding of the patient's condition,to assess the risk of treatment,and to treat with ozagrel sodium and batroxobin.
作者
龙晓艳
柘晓宁
汤利
Long Xiao-yan;Zhe Xiao-ning;Tang Li(Department of Neurology,Panzhihua Second People's Hospital,Sichuan,Panzhihua 617067,Sichuan Province,China)
出处
《中外医药研究》
2023年第2期6-8,共3页
JOURNAL OF CHINESE AND FOREIGN MEDICINE AND PHARMACY RESEARCH
