摘要
JAK/STAT信号通路在生物体中广泛存在,通过介导各种细胞因子的分泌发挥相应的生物学效应,并可通过诱导白介素-6分泌增多参与高血压的形成。探究JAK/STAT通路与高血压的联系成为新的研究热点,并有助于寻找新的药物治疗靶点。
The JAK/STAT signaling pathway is widely existed in organisms,and plays a corresponding biological effect by mediating secretion of various cytokines,and is involved in the formation of hypertension by inducing increased interleukin-6 secretion.Exploring the association between the JAK/STAT pathway and hypertension has become a new research hotspot and contributes to the search for new therapeutic targets for antihypertensive drugs.
作者
朱瑞松
石静
薛红杰
孔一慧
ZHU Rui-song;SHI Jing;XUE Hong-jie;KONG Yi-hui(Department of Cardiology,First Affiliated Hospital of Harbin Medical University,Harbin,Heilongjiang,150001,China)
出处
《心血管康复医学杂志》
CAS
2023年第3期244-247,共4页
Chinese Journal of Cardiovascular Rehabilitation Medicine
基金
国家自然科学基金项目(81900374)。
