摘要
目的分析关节镜清理术联合富血小板血浆(platelet-rich plasma,PRP)、医用臭氧应用于膝骨关节炎(knee osteoarthritis,KOA)患者的疗效。方法随机选取2021年1月—2022年1月包头医学院第一附属医院骨科收治的50例骨关节炎患者为研究对象,随机分为甲组(n=25)与乙组(n=25),两组患者均由同一术者行关节镜清理术,术后甲组行PRP注射,乙组行医用臭氧注射,患者定期随访,记录术前、术后1、3、6个月的膝关节Lysholm评分、WOMAC指数。结果术前,两组患者WOMAC和Lysholm评分比较,差异无统计学意义(P>0.05)。甲组术后1、3个月的WOMAC评分分别为(35.76±3.26)分、(28.16±2.23)分,高于乙组的(29.60±3.55)分、(24.48±3.62)分,但术后6个月甲组WOMAC评分(17.36±1.44)分低于乙组(22.12±2.33)分,差异有统计学意义(t=6.396、4.329、8.681,P<0.05)。甲组术后1、3个月的Lysholm评分低于乙组,但术后6个月Lysholm评分高于乙组,差异有统计学意义(P<0.05)。结论关节镜清理术联合富血小板血浆及医用臭氧均可减轻膝关节骨关节炎的症状,改善关节功能,但术后医用臭氧较PRP能够更快缓解患者症状,短期疗效较好,在术后6个月时,术后PRP疗效开始优于医用臭氧,更明显地缓解患者骨关节炎症状。
Objective To analyze the mid-term curative effect of arthroscopic debridement combined with plateletrich plasma(PRP)and medical ozone on patients with knee osteoarthritis(KOA).To provide relevant data for clinical selection of KOA treatment.Methods Fifty patients with osteoarthritis admitted to the Orthopedics Department of the First Affiliated Hospital of Baotou Medical College from January 2021 to January 2022 were randomly selected as the research subjects.They were randomly divided into group A(n=25)and group B(n=25).Both groups of patients underwent arthroscopic debridement by the same surgeon.After surgery,group A received PRP injection and group B received medical ozone injection.Patients were regularly followed up,and Lysholm scores and WOMAC index of the knee joint were recorded before and 1,3,and 6 months after surgery.Results Before surgery,there was no statistically significant difference in WOMAC and Lysholm scores between the two groups of patients(P>0.05).The WOMAC scores of Group A at 1 and 3 months after surgery were(35.76±3.26)points and(28.16±2.23)points,higher than those of Group B at(29.60±3.55)points and(24.48±3.62)points,respectively.However,the WOMAC scores of Group A at 6 months after surgery were(17.36±1.44)points lower than that of Group B of(22.12±2.33)points,the difference was statistically significant(t=6.396,4.329,8.681,P<0.05).The Lysholm score of Group A was lower than those of Group B at 1 and 3 months after surgery,but the Lysholm score was higher than that of Group B at 6 months after surgery,the difference was statistically significant(P<0.05).Conclusion Arthroscopic debridement combined with plateletrich plasma and medical ozone can alleviate the symptoms of knee osteoarthritis and improve joint function.However,postoperative medical ozone can faster alleviate patient symptoms than PRP,with better short-term efficacy.At 6 months after surgery,postoperative PRP begins to have better efficacy than medical ozone,more significantly alleviating the symptoms of osteoarthritis in patients.
作者
曹利民
王玉林
刘有才
CAO Limin;WANG Yulin;LIU Youcai(Baotou Medical College,Inner Mongolia University of Science and Technology,Baotou,Inner Mongolia Autonomous Region,014000 China;Department of Orthopedics,the First Affiliated Hospital of Baotou Medical College,Baotou,Inner Mongolia Autonomous Region,014000 China)
出处
《中外医疗》
2023年第10期5-9,共5页
China & Foreign Medical Treatment
