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经椎间孔腰椎椎间融合后融合器后移的危险因素分析 被引量:1

Risk factors for cage retropulsion following transforaminal lumbar interbody fusion
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摘要 背景:既往文献报道融合器与原位置相比移位超过2 mm即认为融合器后移。目前临床观察发现导致融合器移位的因素较为复杂,这些因素与融合器后移的关联目前还无法明确。目的:探讨经椎间孔腰椎椎间融合后融合器后移的危险因素。方法:回顾性分析2020年2月至2022年2月采用椎间融合器行经椎间孔腰椎椎间融合手术的200例患者,根据术后(拔除引流管第2天)及术后1,3,6,12个月椎体融合器后缘距椎体后缘距离,将患者分为融合器后移组(≥2 mm)与融合器未后移组(<2 mm),对可能影响融合器后移的因素如年龄、性别、体质量指数、骨密度、手术时间、出血量、终板损伤、术前术后椎间隙高度、cage置入深度、cage大小、节段性前凸角等进行单因素与Logistic回归分析。结果与结论:①15例发生融合器后移(15/200);两组患者年龄、体质量指数、手术时间等差异无统计学意义;②单因素分析结果为椎间隙高度差、佩戴支具时间、节段性前凸角差、骨密度、年龄与融合器后移有关;③Logistic回归分析结果为cage大小、终板损伤情况及cage置入的位置是融合器后移的危险因素;④结果说明,融合器后移受节段性前凸角差、骨密度、cage大小、终板损伤情况、佩戴支具时间及cage置入的深度等因素影响。 BACKGROUND:Previous literature reported that the fusion cage moved more than 2 mm from its original position,which means that the fusion cage moved backward.At present,clinical observation has found that the factors leading to the displacement of the fusion cage are complex,and the relationship between these factors and the cage retropulsion is not clear.OBJECTIVE:To explore the risk factors related to cage retropulsion after lumbar interbody fusion.METHODS:Retrospective analysis was conducted in 200 patients who underwent transforaminal lumbar interbody fusion surgery with a polyetheretherketone interbody fusion from February 2020 to February 2022.According to the distance from the posterior edge of the vertebral fusion cage to the posterior edge of the vertebral body after the operation(the second day after the removal of the drainage tube)and 1,3,6 and 12 months after the operation,patients were divided into cage retropulsion group(≥2 mm)and cage non-retropulsion group(<2 mm).The factors that may affect cage retropulsion,such as age,gender,body mass index,bone mineral density,operation time,bleeding,endplate injury,preoperative and postoperative interbody height,cage implantation depth,cage size,and segmental anterior convexity angle,were analyzed by univariate and logistic regression analysis.RESULTS AND CONCLUSION:(1)Posterior displacement of the fusion cage occurred in 15 cases(15/200).The differences in basic information such as age and body mass index between the two groups were not statistically significant.(2)The results of the univariate analysis were that gap height difference,time to wear a brace,segmental anterior convexity angle difference,bone mineral density,and age were related to posterior migration of the cage.(3)The results of logistic regression analysis were that cage size,endplate injury condition,and depth of cage implantation were risk factors for cage retropulsion.(4)These findings suggest that cage retropulsion after lumbar interbody fusion is caused by multiple factors,including segmental anterior convexity angle difference,bone mineral density,cage size,endplate damage,time to wear a brace,and depth of cage implantation.
作者 席金涛 鲁齐林 汪洋 王小娟 吕鹏 陈龙 石震 谢维 竺义亮 李绪贵 Xi Jintao;Lu Qilin;Wang Yang;Wang Xiaojuan;Lyu Peng;Chen Long;Shi Zhen;Xie Wei;Zhu Yiliang;Li Xugui(Hubei 672 Orthopedics Hospital of Integrated Chinese&Western Medicine/Affiliated Hospital of Wuhan Institute of Physical Education,Wuhan 430070,Hubei Province,China)
出处 《中国组织工程研究》 CAS 北大核心 2024年第9期1394-1398,共5页 Chinese Journal of Tissue Engineering Research
关键词 经椎间孔腰椎椎间融合术 融合器 后移 腰椎 危险因素 transforaminal lumbar interbody fusion cage retropulsion lumbar vertebra risk factor
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