摘要
目的探讨子宫内膜癌平均发病年龄及国内外差异。方法选择Pubmed、万方数据库、维普信息资源系统、中国知网等,提取子宫内膜癌相关临床研究数据,通过频次分析、聚类分析等数据挖掘方法,比较国内外子宫内膜癌平均发病年龄的差异。结果筛选出符合纳入标准的文献280篇,频次分析发现子宫内膜癌的平均发病年龄,中国人群大部分集中于57岁以下,而欧美国家人群主要集中于57岁以上。通过聚类分析发现,中国的平均发病年龄与多数亚洲国家聚为一类,而欧美国家与澳洲国家聚为另一类。通过对国内及国外文章进行分析发现,子宫内膜癌平均发病年龄随年份变化无明显上升或下降趋势。结论子宫内膜癌平均发病年龄在不同国家地区之间存在差异,亚洲人群发病年龄明显早于欧美人群,中国人群子宫内膜癌平均发病年龄为54岁,子宫内膜癌的发病尚未见年轻化趋势。
Objective To explore the average age at onset of endometrial cancer(EC)and the differences between domestic and international factors.Methods Pubmed,Wanfang Database,VIP Information Resource System,and China National Knowledge Infrastructure(CNKI)were selected to extract clinical research data related to EC.Through data mining methods such as frequency analysis and cluster analysis,we compared the differences in the average age of onset of EC between domestic and foreign countries.Results A total of 280 articles that met the inclusion criteria were selected,and frequency analysis found that the average age of onset of EC in the Chinese population was mostly concentrated under 57 years old,while in European and American countries,it was mainly concentrated above 57 years old.Through cluster analysis,it was found that the average age of onset in China was clustered in one category with most Asian countries,while European and American countries and Australian countries were clustered in another category.Through analysis of domestic and foreign articles,it was found that the average age of onset of EC did not show a significant upward or downward trend with years.Conclusions There are differences in the average onset age of EC among different countries and regions.The onset age of EC in Asian populations is significantly earlier than that in European and American populations.The average onset age of EC in Chinese populations is 54 years old,and there is no trend towards a younger onset of EC.
作者
李小毛
王佳
邱素苈
郎景和
Li Xiaomao;Wang Jia;Qiu Suli;Lang Jinghe(Department of Gynecology,the Third Affiliated Hospital of Sun Yat-sen University,Guangzhou 510630,China;Department of Gynecology,Peking Union Medical College Hospital,Beijing 100730,China)
出处
《中国医师杂志》
CAS
2023年第5期652-655,共4页
Journal of Chinese Physician
基金
广东省自然科学基金(2021A1515011542)。
