摘要
脑心清片用于缺血性脑血管病具有良好的临床疗效及安全性。在对临床医生进行问卷调查和脑心清片现有文献系统回顾的基础上,采用国际临床医学专家共识研制方法,基于现有最佳证据,充分结合专家经验,遵循“循证为主,共识为辅,经验为鉴”的原则,国内31位中、西医临床与方法学、药学等多学科专家共同研制该共识,旨在进一步提高临床医生对该药的认识,更好地指导其临床合理用药。该共识采用国际公认的证据分级推荐标准:GRADE分级。专家共识意见的形成采用名义组法,主要考虑证据质量、疗效、安全性、患者可接受性及其他等5个方面的因素。如果证据充分则形成“推荐意见”,采用GRADE网格计票规则;如果证据不充分,则形成“共识建议”,采用多数计票规则。该共识对脑心清片用于缺血性脑血管病之脉络瘀阻证的疗效、用法用量、疗程进行了推荐或建议,并完善了安全性信息,并通过专家会议以及函审的方式,在全国范围内进行征求意见和同行评议,可为临床的合理用药提供参考。
Naoxinqing Tablet(脑心清片)has good clinical efficacy and safety when used in ischemic cerebrovascular disease.Based on questionnaire investigation of doctors and a systematic review of research literature on Naoxinqing Tablet,using international clinical practice guidelines'developing methods,with the best available evidence and fully combining experts'experience,and following the principle of"evidence-based,consensus-based and experience-based",the expert consensus statement on Naoxinqing Tablet in clinical practice was developed by 31 multidisciplinary experts from the nationwide,aimed at guiding and standardizing the rational use of Naoxinqing Tablet.The expert consensus adopts internationally recognized recommendation criteria for classification of evidence:GRADE.The formation of expert consensus adopted the nominal group technique.Five main considerations were quality of evidence,curative effect,safety,patient acceptability and other factors.If there was sufficient evidence,a"recommendation"was formed,using GRADE grid voting rule.If there was no sufficient evidence,a"consensus opinion"was formed,using majority counting rule.The expert consensus focused on the indication,usage and dosage,and safety of Naoxinqing Tablet for ischemic cerebrovascular disease(arteries and veins stasis syndrome).Through experts'meetings and correspondence,a nationwide consultation and peer review was conductedto provide guidance and reference for the rational use of Naoxinqing Tablet.
作者
蔡业峰
王新志
中华中医药学会脑病分会代表编制组
CAI Yefeng;WANG Xinzhi;Representative Preparation Group ofBrain Diseases Branch of Chinese Society of Traditional Chinese Medicine(Guangdong Provincial Hospital of Chinese Medicine,Guangzhou 510000,Guangdong,China;The First Affiliated Hospital of Henan University of Chinese Medicine,Zhengzhou 450000,Henan,China;不详)
出处
《中华中医药学刊》
CAS
北大核心
2023年第5期247-253,共7页
Chinese Archives of Traditional Chinese Medicine
关键词
脑心清片
缺血性脑血管病
脉络瘀阻证
专家共识
Naoxinqing Tablet(脑心清片)
ischemic cerebrovascular disease
arteries and veins stasissyndrome
expert consensus
