摘要
患者男,48岁。双下肢红斑、水疱、结节伴瘙痒40年,加重10年。皮肤科情况:双侧足背、胫前红斑、水疱、瘢痕及粟丘疹,可见甲营养不良伴部分趾甲脱落,尼氏征阴性。皮损组织病理示:表皮角化过度,表皮下见一裂隙,真皮浅层细血管增生伴纤维细胞增生,裂隙旁见粟丘疹样角质囊肿。诊断:胫前型营养不良型大疱性表皮松解症。经中西医结合治疗后病情缓解,现仍在随访中。
A 48-year-old male showed erythema,blisters,nodules on double lower extremities with itching for 40 years,and the leisions aggravated for 10 years.Erythema,blisters,scars and milia presented on dorsal and front of calves,nail malnutrition was found and some toenails fall off.Nikolsky's sign was negative.Histopathological results showed excessive keratinization of the epidermis,cleft under theepidermis,lymphocytic infiltration of the dermis,hyperplasia of superficial vascular and fibrous tissue,and milia like keratin cyst.Diagnosis of Pretibial epidermolysis bullosa was made.The patient was treated with combined treatment of traditional and Western medicine and the lesions improved gradually.The patient was still followed up.
作者
邹旭辉
杨瑾
冯天宇
乔博亚
欧阳晓勇
王丽芬
杨雪松
ZOU Xuhui;YANG Jin;FENG Tianyu;QIAO Boya;OUYANG Xiaoyong;WANG Lifen;YANG Xuesong(Department of Dermatology,The First Affiliated Hospital of Yunnan Chinese Medicine University,Kunming 650021,China)
出处
《中国皮肤性病学杂志》
CAS
CSCD
北大核心
2023年第5期557-559,562,共4页
The Chinese Journal of Dermatovenereology
基金
云南省院士(专家)工作站项目-云南省冯素英专家工作站(202105AF150035)。
关键词
营养不良型大疱性表皮松解症
胫前型
中西医结合
治疗
Dystrophic epidermolysis bullosa
Pretibial
Integrated traditional Chinese medicine&western medicine
Treatment
