摘要
目的遴选并总结国内外胶质母细胞瘤电场治疗患者皮肤管理的相关最佳证据,为临床决策提供参考。方法计算机检索Cochrane Library、UpToDate、PubMed、Embase、CINAHL、Web of Science、中国知网、万方数据库、维普网、中国生物医学文献服务系统、指南网及专业协会网站,纳入胶质母细胞瘤电场治疗患者皮肤管理相关的临床实践指南、专家共识、临床决策、系统评价及证据总结等,检索时限均为建库至2022年3月31日。由2名研究员独立对文献进行质量评价及证据提取。结果共纳入9篇文献,包括指南2篇、专家共识4篇、系统评价2篇、临床决策1篇,围绕危险因素、护理评估、预防性干预措施、药物治疗、皮肤不良反应及处理等5个方面形成31条最佳证据。结论本研究总结了胶质母细胞瘤电场治疗患者皮肤管理的最佳证据,医护人员应根据临床情景及患者实际情况充分评估患者的皮肤状况,做好皮肤管理,减少患者皮肤损伤的发生率。
Objective To select and summarize the best evidence related to skin management in glioblastoma patients treated with tumor treating fields(TTFields)at home and abroad,so as to provide reference for clinical decision-making.Methods Cochrane Library,UpToDate,PubMed,Embase,CINAHL,Web of Science,CNKI,Wanfang Database,VIP,SinoMed,Guideline Network and professional association websites were searched by computer.Clinical practice guidelines,expert consensus,clinical decision-making,systematic review and evidence summary related to skin management in patients with glioblastoma treated with TTFields were included,and the retrieval time was from establishment of databases to March 31,2022.Two researchers independently evaluated the quality of literature and extracted evidence.Results A total of 9 literatures were included,including 2 guidelines,4 expert consensus,2 systematic reviews and 1 clinical decision-making.A total of 31 pieces of best evidence were formed from 5 aspects,including risk factors,nursing evaluation,preventive intervention measures,drug therapy and adverse skin reactions and treatment.Conclusions This study summarizes the best evidence for skin management of glioblastoma patients treated with TTFields.Medical staff should fully evaluate the skin condition of patients according to the clinical scenario and the actual situation of patients and do a good job in skin management to reduce the incidence of skin injury of patients.
作者
刘冉冉
袁巧玲
Liu Ranran;Yuan Qiaoling(Department of Neurosurgery,Beijing Tiantan Hosipital,Capital Medical University,Beijing 100070,China)
出处
《中华现代护理杂志》
2023年第16期2131-2137,共7页
Chinese Journal of Modern Nursing
关键词
胶质母细胞瘤
电场治疗
不良反应
皮肤管理
循证护理
Glioblastoma
Tumor treating fields
Adverse reactions
Skin management
Evidence-based nursing