摘要
目的探讨抑郁症患者采用疏肝解忧汤与帕罗西汀联合治疗的效果。方法选取2020年3月至2022年2月在焦作市精神病院接受治疗的84例抑郁症患者,根据随机数表法分为研究组(n=42)与对照组(n=42),对照组采用帕罗西汀治疗,研究组采用疏肝解忧汤+帕罗西汀治疗,比较两组临床疗效、抑郁程度、中医证候积分、血液流变学指标。结果研究组治疗有效率(95.24%)高于对照组(76.19%);治疗后两组汉密尔顿抑郁量表(HAMD)评分低于治疗前,且研究组评分低于对照组;治疗后两组中医证候积分低于治疗前,且研究组积分低于对照组;治疗后两组血液流变学指标低于治疗前,且研究组低于对照组,差异有统计学意义(P<0.05)。结论疏肝解忧汤+帕罗西汀应用于抑郁症患者治疗中,可提高临床疗效,降低抑郁程度,缓解临床症状,改善血液流变学指标。
Objective To explore the effect of combined treatment of Shugan Jieyu decoction and paroxetine in patients with depression.Methods A total of 84 patients with depression who were treated in Jiaozuo Psychiatric Hospital from March 2020 to February 2022 were selected,by random number table method,they were divided into the study group(n=42)and the control group(n=42).Paroxetine was treated in the control group,Shugan Jieyu decoction combined with paroxetine was treated in the study group.The clinical efficacy,depression degree,TCM syndrome score and hemorheology index of the two groups were compared.Results In the total treatment effective rate,in comparision of the control group(76.19%),the study group(95.24%)was higher.After treatment,the scores of HAMD in both groups were decreased,and compared with the control group,the study group was lower.After treatment,the TCM syndrome scores in both groups were decreased,and compared with the control group,the study group was lower.After treatment,the hemorheology index in both groups were decreased,and compared with the control group,the study group was lower,with significant differences(P<0.05).Conclusion Shugan Jieyu decoction combined with paroxetine can improve the clinical efficacy,reduce the degree of depression,relieve the clinical symptoms and improve the hemorheology indexes in the treatment of depression patients.
作者
李小芬
李晶晶
常树勋
LI Xiaofen;LI Jingjing;CHANG Shuxun(Department of Integrated Traditional Chinese and Western Medicine,Jiaozuo Psychiatric Hospital,Jiaozuo Henan 454001,China;Department of Teaching Office,The First Affiliated Hospital of Henan Polytechnic University,Jiaozuo Henan 454001,China;Department of Anorectal,Jiaozuo First People's Hospital,Jiaozuo Henan 454002,China)
出处
《临床研究》
2023年第7期87-89,共3页
Clinical Research
