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新型携^(125)I粒子鼻饲营养管治疗食管癌患者周围辐射剂量率的监测

Monitoring of peripheral radiation dose rates in patients with esophageal cancer treated with a new nasal nutrition tube carrying^(125)I seeds
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摘要 目的:监测新型携^(125)I粒子营养管置入食管癌患者术后周身辐射剂量率,进而指导医护防护。方法:对2019年7月-2021年9月间接受新型携^(125)I粒子鼻饲营养管(简称粒子营养管)置入的30名患者在未辐射防护和0.25 mm铅衣防护状态下,分别于术后即刻和6周,监测胸骨水平前、后、左、右四个方向不同距离(距皮肤表面0.0、0.2、0.4、0.6、0.8和1.0 m)的辐射剂量率,并将点测量值与空气本底值比较。结果:0.25 mm铅衣防护下,术后即刻后、左、右方位及术后6周各方位0.0 m辐射剂量监测值与空气本底值相比差异均无统计学意义(P均>0.05);无防护状态下即刻,在粒子营养管置入患者的前、后、左、右1.0、0.6、0.8、0.8 m处,剂量率与本底值比较,差异无统计学意义(P>0.05);无防护状态下6周后,患者前、后、左、右0.8、0.4、0.6、0.6 m处,剂量率与本底值比较,差异无统计学意义(P>0.05)。结论:在对接受粒子营养管治疗的患者进行诊疗时,应保持1米以上的安全距离,近距离接触时应选用铅衣等防护用品,减少辐射损伤。 Objective:To detect the radiation dose rate around the body of patients with esophageal cancer after implantation of^(125)I seeds nutrition tube,to guide the medical protection work.Methods:30 patients received^(125)I seeds nutrition tubes between July 2019 and September 2021were underwent radiation dose rate monitoring in four directions(anterior,posterior,left,right)at the state of non-radiation protection or 0.25 mm lead clothing protection.The measurement times were set at the point of the day after surgery and post-6-week,while the radiation dose rate was measured at 0.0 m,0.2 m,0.4 m,0.6 m,0.8 m,and 1.0 m to the skin surface in four directions.The values measured at each point were compared with the background value.Results:At the state of 0.25 mm lead clothing protection,the differences in the radiation dose rate at 0.0m to the skin surface between all the directions at both measuring points except anterior direction at the day after surgery and the background value were not statistically different(P>0.05).At the state of non-radiation protection,the differences in radiation dose rate between 1.0 m of anterior,0.6 m of posterior,0.8 m of left and 0.8 m of right and the background value were not statistically different at the day after surgery(P>0.05).The differences in radiation dose rate between 0.8 m of anterior,0.4 m of posterior,0.6 m of left and 0.6 m of right and the background value were not statistically different post-6-week(P>0.05).Conclusion:It is safe for medical staff to maintain a distance of more than 1 meter for the diagnosis and treatment of patients with esophageal cancer after implantation of ^(125)I seeds nutrition tube.And it is necessary for medical staff to select protective equipment when in close contact with them.
作者 徐苗 田川 焦德超 许凯豪 刘一铭 孙莉莉 贾自玲 余珍 韩新巍 李亚华 XU Miao;TIAN Chuan;JIAO Dechao;XU Kaihao;LIU Yiming;SUN Lili;JIA Ziling;YU Zhen;HAN Xinwei;LI Yahua(Department of Radiation Intervention,the First Affiliated Hospital of Zhengzhou University,Henan Zhengzhou 450052,China;Department of Comprehensive Medicine,the First Affiliated Hospital of Zhengzhou University,Henan Zhengzhou 450052,China)
出处 《现代肿瘤医学》 CAS 北大核心 2023年第14期2655-2660,共6页 Journal of Modern Oncology
基金 河南省医学科技攻关计划省部共建青年项目(编号:SB201902014)。
关键词 ^(125)I放射性粒子 食管癌 辐射剂量 辐射监测 ^(125)I radioactive seeds esophageal cancer radiation dose radiation monitoring
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