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右美托咪定对小儿患者七氟醚复合骶管阻滞麻醉苏醒期躁动的影响

Effect of Dexmedetomidine on Agitation During Recovery Period of Sevoflurane Combined with Sacral Canal Block Anesthesia in Children
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摘要 目的探讨小儿患者七氟醚复合骶管阻滞麻醉后,右美托咪定对其麻醉苏醒期躁动的影响。方法随机选取2020年3月—2022年1月张掖市第二人民医院收治的80例使用七氟醚复合骶管阻滞麻醉的手术患儿,随机抽签分为两组,每组40例。对照组在麻醉苏醒期使用生理盐水,观察组使用右美托咪定,对比两组炎症反应、应激反应、躁动评分、心率等指标。结果观察组手术结束即刻心率(68.37±5.62)次/min、平均动脉压(112.64±10.52)mmHg,以及麻醉苏醒期NO(31.52±3.26)μmol/L等水平均优于对照组,差异有统计学意义(t=8.995、7.663、28.066,P<0.05)。结论小儿患者七氟醚复合骶管阻滞麻醉苏醒期,使用右美托咪定能够减少躁动,稳定生命体征,改善应激、炎症反应,保障手术安全性,达到镇静效果。 Objective To investigate the effect of dexmedetomidine on agitation during anesthesia recovery in children after sevoflurane combined with sacral canal block anesthesia.Methods 80 children treated with sevoflurane combined with sacral canal block anesthesia in Zhangye Second People's Hospital from March 2020 to January 2022 were randomly selected and divided into two groups with 40 cases in each group.Normal saline was used in the control group and dexmedetomidine was used in the observation group.The inflammatory response,stress response,agitation score,heart rate and other indexes were compared between the two groups.Results Heart rate(68.37±5.62)times/min,mean arterial pressure(112.64±10.52)mmHg immediately after operation,and NO(31.52±3.26)μmol/L during anesthesia and recovery in the observation group were better than those in the control group,and the difference was statistically significant(t=8.995,7.663,28.066,P<0.05).Conclusion In pediatric patients with sevoflurane combined with sacral canal block anesthesia during the recovery period,dexmedetomidine can reduce agitation,stabilize vital signs,improve stress and inflammation,ensure surgical safety,and achieve sedation effect.
作者 宁军 王宏 NING Jun;WANG Hong(Department of Anesthesia and Perioperative Medicine,Zhangye Second People's Hospital,Zhangye,Gansu Province,734000 China)
出处 《中外医疗》 2023年第16期106-110,共5页 China & Foreign Medical Treatment
基金 张掖市市级科技计划B类计划项目(ZY2022BJ19)。
关键词 右美托咪定 七氟醚 骶管阻滞麻醉 麻醉苏醒期 躁动 应激反应 炎症反应 Dexmedetomidine Sevoflurane Sacral canal block anesthesia Anesthesia recovery period Restlessness Stress response Inflammatory response
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