摘要
目的探讨出生至学龄前儿童体重变化与血压的关系,并评估母乳喂养在其中的作用。方法2018年4~5月间,选取厦门市思明区8所幼儿园1233名3~6岁儿童为研究对象,对儿童进行血压测量、体格测量和问卷调查。依据研究对象出生体重和当前BMI状态分为4组:正常出生体重-正常BMI组、高出生体重-正常BMI组、正常出生体重-超重/肥胖组、高出生体重-超重/肥胖组。采用Logistic回归分析各组高血压发生风险。结果正常出生体重-超重/肥胖组和高出生体重-超重/肥胖组高血压检出率、SBP和DBP水平均显著高于另外两组。以正常BMI组为参照,超重组和肥胖组发生高血压的调整后OR值分别为2.05(1.25~3.37)和2.24(1.69~2.98)。按母乳喂养时长分层后,以正常出生体重-正常BMI组为参照,在母乳喂养时长0~5月和≥6月的儿童中,正常和高出生体重-超重/肥胖组发生高血压的调整后OR值分别为2.84(1.57~5.15)和1.53(1.21~1.93)。结论无论出生体重高低,发展为超重/肥胖的学龄前儿童,其高血压检出率、SBP和DBP水平均显著高于出生至学龄前体重一直正常和高出生体重转变为正常BMI者。较长时间的母乳喂养(≥6月)可能对降低当前超重/肥胖者发生高血压的风险起到一定作用。
Objective To explore the relationship between weight change from birth to preschool age and blood pressure of preschoolers,and to evaluate the role of breastfeeding in this relationship.Methods A cross-sectional study was conducted from April to May 2018.Totally,1233 children aged 3-6 years from 8 kindergartens were selected as the subjects.The data collected during the study include information on the children’s blood pressure,physical measurements,and health-rela ted behaviors questionnaires.The subjects were divided into four groups according to their birth weight and current body mass index(BMI)status:normal birth weight-normal BMI group,high birth weight-normal BMI group,normal birth weight-overweight/obesity group,high birth weight-overweight/obesity group.Logistic regression was used to analyze the relationship between weight change and the risk of hypertension.Results The prevalence of hypertension,systolic pressure(SBP)and diastolic pressure(DBP)levels in individuals of normal birth weight-overweight/obesity group and high birth weight-overweight/obesity group were significantly higher than those in the other two groups.Compared with the normal BMI group,the overweight group and obesity group had significantly higher risk of developing hypertension,the adjusted ORs were 2.05(1.25-3.37)and 2.24(1.69-2.98),respectively.After stratification according to breastfeeding duration,compared with the normal birth weight-normal BMI group,it was found that in children who were breasted for 0-5 months and≥6 months,the adjusted ORs of hypertension in normal and high birth weight-overweight/obesity group were 2.84(1.57-5.15)and 1.53(1.21-1.93),respective-ly.Conclusion Irres pective of birth weight,preschoolers who developed overweight/obesity were found to have a higher preva-lence of hypertension,higher SBP and DBP levels than those who had normal weight from birth to preschool age and who had changed from high birth weight to normal BMI Longer breastfeeding duration(≥6 months)may play a role in reducing the risk of hy pertension in preschoolers with over weight/obesity.
作者
汪桂艳
陈晶
熊永强
赵旭
赖智双
钟红秀
Wang Guiyan;Chen Jing;Xiong Yongqiang(Department of Healthcare,Women and Children's Hospital,School of Medicine,Xiamen University,X iamen 361003,China;Department of Child Healthcare,Women and Children's Hospital,School of Medicine,Xiamen University,X iamen 361003,China)
出处
《华中科技大学学报（医学版）》
CAS
CSCD
北大核心
2023年第3期345-350,共6页
Acta Medicinae Universitatis Scientiae et Technologiae Huazhong
基金
福建省厦门市科技计划项目(No.3502Z20164029)。
