摘要
目的探讨增强CT在儿童肾透明细胞肉瘤(CCSK)与肾母细胞瘤(WT)鉴别诊断中的临床价值。方法选60例疑似CCSK/WT患儿均进行增强CT、病理学检查,对比2项检验结果,并分析增强CT的检查征象。结果经病理切片免疫组织化学染色法诊断,CCSK患儿有23例(38.33%),均为单侧发病,左侧17例,右侧6例,瘤体昀大径5.26~15.62cm,未发现转移病灶;WT患儿有37例(61.67%),均为单侧发病,左侧21例,右侧16例,瘤体昀大径7.14~20.14cm,未发现转移病灶。根据增强CT结果总结出5个重要征象(即钙化灶、瘤内出血灶、坏死或囊变、肿块边缘小囊征CCSK、WT),它们之间对比无差异(P>0.05),虎斑样条纹征在WT中的占比高于在CCSK中的占比(P<0.05)。结论增强CT在诊断鉴别儿童CCSK与WT时,具有显著的临床价值,有利于疾病的确诊和及早治疗。
Objective To investigate the clinical value of enhanced CT in the differential diagnosis of renal hyaluronsarcoma(CCSK)and nephroblastoma(WT)in children.Methods 60 suspected CCSK/WT children were admitted in our hospital.All the children were examined by enhanced CT and pathology.The results of the two tests were compared and the signs of enhanced CT were analyzed.Results 23 cases(38.33%)were diagnosed as CCSK by immunohistochemical staining of pathological sections,all of them had unilateral disease,17 cases were on the left side and 6 cases were on the right side,the maximum diameter of the tumor was 5.26~15.62cm,and no metastatic lesions were found.There were 37 cases(61.67%)of WT,all of them had unilateral disease,21 cases on the left side and 16 cases on the right side,the maximum diameter of the tumor was 7.14~20.14cm,and no metastatic lesions were found.According to the results of enhanced CT,five important signs of diagnosis were summarized.Among them,calcification,intratumoral hemorrhage,necrosis or cystic degeneration,and small cyst at the edge of the mass showed no difference between CCSK and WT(P>0.05).The proportion of upper CCSK was higher than that of WT(P<0.05).Conclusion Enhanced CT has significant clinical value in the diagnosis and differentiation of CCSK and WT in children,which is helpful for the diagnosis and early treatment of the disease.
作者
陈巧菊
李跃军
CHEN Qiaoju;LI Yuejun(Department of Imaging,Kaifeng Children’s Hospital,Kaifeng,Henan 475000,China;Department 1 of Bone Disease and Bone Tumor,Zhengzhou Orthopaedic Hospital.Zhengzhou,Henan 450052,China)
出处
《生物医学工程学进展》
CAS
2023年第2期188-191,共4页
Progress in Biomedical Engineering
基金
河南医学科技攻关计划项目(LHGJ202004078)。
关键词
原发性肝癌
精准诊断
术前诊断
CT
MRI
Primary Liver Cancer
Accurate Diagnosis
Preoperative Diagnosis
CT
MRI
