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术前口服碳水化合物在甲状腺癌手术中的应用研究

Application of preoperative oral carbohydrates in thyroid cancer surgery
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摘要 目的 探讨甲状腺癌患者术前口服碳水化合物的疗效与安全性。方法 选取2021年1月至2022年3月该院行甲状腺癌手术患者134例,根据入院时间将其分为研究组(70例)和对照组(64例)。对照组采用常规禁食禁饮方法,研究组在常规禁食禁饮基础上联合术前口服碳水化合物方法。比较2组术后康复情况、围手术期血液指标及并发症发生情况。结果 研究组术后首次排气时间、首次排便时间、住院时间及住院总费用均优于对照组,差异有统计学意义(P<0.05)。2组术前空腹血糖、白细胞计数、C-反应蛋白水平比较,差异无统计学意义(P>0.05)。研究组术后1、3 d时空腹血糖、白细胞计数、C-反应蛋白水平均低于对照组,差异有统计学意义(P<0.05)。研究组术后恶心呕吐发生率低于对照组,差异有统计学意义(P<0.05)。2组术后手足麻木、出血窒息、声嘶、饮水呛咳、乳糜瘘发生率比较,差异无统计学意义(P>0.05)。结论 甲状腺癌患者术前口服碳水化合物能减轻围手术期应激反应,改善胰岛素抵抗,降低术后恶心呕吐发生率,促进患者康复,同时可缩短住院时间,节省住院费用。 Objective To explore the efficacy and safety of preoperative oral carbohydrates in patients with thyroid cancer.Methods A total of 134 patients who underwent thyroid cancer surgery in the hospital from January 2021 to March 2022 were selected and divided into the study group(70 cases)and the control group(64 cases)based on their admission time.The control group was treated with routine fasting and drinking,while the study group was treated with preoperative oral carbohydrate therapy on the basis of the control group.The postoperative recovery,perioperative blood indicators and incidence of complications were compared between the two groups.Results The first exhaust time,first bowel movement time,hospitalization time,and total hospitalization cost after surgery in the study group were better than those in the control group,with statistically significant differences(P<0.05).There were no significant differences in the levels of fasting blood glucose,white blood cell count and C-reactive protein before surgery between the two groups(P>0.05).The fasting blood glucose,white blood cell count,and C-reactive protein levels at 1,3 days after surgery in the study group were lower than those in the control group,with statistically significant differences(P<0.05).The incidence of postoperative nausea and vomiting in the study group was lower than that in the control group,and the difference was statistically significant(P<0.05).There were no statistically significant differences in the incidence of postoperative numbness of hands and feet,bleeding and suffocation,hoarseness,coughing due to drinking water,and chylous fistula between the two groups(P>0.05).Conclusion Preoperative oral carbohydrates in thyroid cancer patients can reduce perioperative stress response,improve insulin resistance,reduce the incidence of postoperative nausea and vomiting,promote patients′recovery,shorten hospitalization time,and save hospitalization costs.
作者 钱雪蔚 柯婧婧 QIAN Xuewei;KE Jingjing(Department of General Surgery,the Affiliated Tumor Hospital of Nantong University,Nantong,Jiangsu 226000,China)
出处 《现代医药卫生》 2023年第13期2228-2231,共4页 Journal of Modern Medicine & Health
关键词 甲状腺癌 碳水化合物 加速康复外科 Thyroid cancer Carbohydrates Accelerated rehabilitation surgery
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