摘要
目的观察内治外灸法治疗阳虚型肝硬化腹水的临床疗效。方法选取80例阳虚型肝硬化腹水患者,随机分为治疗组和对照组,每组40例。对照组给予西医常规治疗,治疗组在此基础上联合中医内治外灸法治疗。比较两组治疗前后中医证候积分、平均腹水消退时间以及治疗前后的腹围、体质量、24 h尿量、肝功能及凝血酶原活动度变化,比较两组临床疗效、不良反应发生率及腹水复发率。结果治疗组总有效率(92.5%)高于对照组(75.0%)(P<0.05)。治疗后,两组中医证候积分均较治疗前下降(P<0.05),且治疗组低于对照组(P<0.05)。治疗组平均腹水消退时间明显低于对照组(P<0.05)。治疗后,两组腹围、体质量较治疗前下降(P<0.05),24 h尿量较治疗前增加(P<0.05);且治疗组优于对照组(P<0.05)。治疗后,两组总胆红素、谷丙转氨酶、谷草转氨酶均下降(P<0.05),胆碱酯酶、白蛋白、凝血酶原活动度均上升(P<0.05);且治疗组优于对照组(P<0.05)。两组不良反应发生率及腹水复发率比较,差异有统计学意义(P<0.05)。结论在西医常规治疗的基础上,内治外灸法治疗阳虚型肝硬化腹水疗效显著,可加速患者腹水消退,改善临床症状,减轻患者病痛,可有效减少不良反应,降低复发率。
Objective To observe the clinical efficacy of internal treatment plus external moxibustion in treating ascites in cirrhosis of Yang deficiency.Method Eighty patients with cirrhosis-induced ascites of Yang deficiency were recruited and randomized into a treatment group and a control group,with 40 cases in each group.The control group was given the conventional Western medicine treatment,based on which the treatment group received additional internal treatment and external moxibustion of traditional Chinese medicine(TCM).The TCM symptom score before and after treatment,average ascites subsidence time,and post-treatment changes in the abdominal circumference,body mass,24 h urine volume,liver function,and prothrombin activity were compared.The clinical efficacy,adverse reaction rate,and ascites recurrence rate were also compared between the two groups.Result The total effective rate in the treatment group(92.5%)was higher than that in the control group(75.0%)(P<0.05).After treatment,the TCM symptom score dropped in both groups(P<0.05)and was lower in the treatment group than in the control group(P<0.05).The average ascites subsidence time was markedly shorter in the treatment group than in the control group (P<0.05). The abdominal circumference and body mass dropped after treatment in the two groups (P<0.05), and the 24 h urine volume increased (P<0.05);the treatment group showed advantages over the control group (P<0.05). After intervention, the levels of total bilirubin, alanine transaminase, and aspartate transaminase decreased in both groups (P<0.05), and the levels of cholinesterase, albumin, and prothrombin activity increased (P<0.05);the treatment group was superior to the control group (P<0.05). The two groups had significant differences in the adverse reaction rate and ascites recurrence rate (P < 0.05). Conclusion On the basis of conventional Western medicine treatment, the combination of internal treatment and external moxibustion can produce significant efficacy in treating ascites in cirrhosis of Yang deficiency;it can accelerate ascites subsidence, improve clinical symptoms, reduce the suffering of the patients, effectively reduce adverse reactions, and lower the recurrence rate.
作者
曹雪艳
李强
何瑾瑜
薛敬东
李粉萍
CAO Xueyan;LI Qiang;HE Jinyu;XUE Jingdong;LI Fenping(Shaanxi Province Hospital of Traditional Chinese medicine,Xi’an 710003,China;Xi’an Hospital of Traditional Chinese Medicine,Xi’an 710000,China)
出处
《上海针灸杂志》
CSCD
2023年第7期683-688,共6页
Shanghai Journal of Acupuncture and Moxibustion
基金
陕西省感染性疾病临床医学研究中心(中西医结合)建设项目(2020LCZX-02)
国家中医药管理局区域中医(肝病)诊疗中心培育单位建设项目[国中医药办医政函(2017)39号]
陕西省中医药管理局-长安医学张氏肝病流派传承工作室建设项目[陕中医药发(2018)40]。
关键词
灸法
药饼灸疗法
内治外灸法
臌胀
肝硬化
腹水
Moxibustion
Medicinal cake-partitioned moxibustion
Internal treatment and external moxibustion therapy
Abdominal tympanites
Liver cirrhosis
Ascites
