摘要
目的:观察疏利三焦法合中药药氧鼻吸入治疗慢性肺心病失代偿期的临床疗效。方法:将60例慢性肺心病失代偿期患者随机分为对照组30例、试验组30例,对照组采用持续低流量吸氧;呋塞米片20mg口服,每日1次;头孢地嗪钠2.0g,每12小时1次;维持水电解质平衡治疗。试验组在对照组治疗方案基础上予小柴胡汤、木防己汤、葶苈子大枣泻肺汤加桃仁化裁口服联合中药(鱼腥草清热利咽合剂)药氧鼻吸入治疗。观察两组临床疗效、入院后第1天及治疗2周后的肺功能测定(FEV_(1)/FVC、FEV_(1))、动脉血气分析及CRP、NT-proBNP、血清总IgE水平。结果:治疗2周后,试验组总有效率为96.7%,高于对照组的60.0%(P<0.05);试验组动脉血气分析指标、CRP、NT-proBNP、血清总IgE、肺功能测定(FEV_(1)/FVC、FEV_(1))改善程度均优于对照组,差异均有统计学意义(P<0.05)。结论:疏利三焦法合中药药氧鼻吸入治疗慢性肺心病失代偿期临床疗效更显著。
Objective:To explore the clinical effect of Shuli San Jiao method and TCM oxygen nasal inhalation in treatment of decompensated period patients with chronic pulmonary heart disease.Methods:Sixty cases of decompensated period patients with chronic pulmonary heart disease were randomly divided into control group(n=30)and experimental group(n=30),the control group received continuous low flow oxygen inhalation,orally taking furosemide tablets 20mg once per day;cefdiazine sodium 2.0g every 12 hours and maintained water and electrolyte balance.On the basis of control group,the experimental group treated with Xiao Chaihu decoction,Mufangji decoction,Tinglizi Dazao Xiefei decoction plus peach kernel combined with TCM(Houttuynia cordata heat clearing and throat promoting mixture)oxygen nasal inhalation.The clinical efficacy and lung function measurements(FEV_(1)/FVC,FEV_(1)),arterial blood gas analysis,CRP,NT-proBNP,total serum IgE on the day after admission and after 2 weeks of treatment were observed.Results:After 2 weeks of treatment,the overall response rate of experimental group was 96.7%,which was higher than 60.0%that of control group(P<0.05);the improvement of arterial blood gas analysis indexes,CRP,NT-proBNP,total serum IgE and lung function measurements(FEV_(1)/FVC,FEV_(1))were better than those of control group,which was statistically significant(P<0.05).Condusion:The combination of Shuli Sanjiao method and TCM oxygen nasal inhalation has a more significant clinical effect on the treatment of chronic pulmonary heart disease in the decompensated period.
作者
程善廷
罗穗萍
黄铭冠
郭丽泉
王嘉锋
江啸锋
CHENG Shan-ting;LUO Sui-ping;HUANG Ming-guan;GUO Li-quan;WANG Jia-feng;JIANG Xiao-feng(Guangzhou Huangpu District Hospital of Traditional Chinese Medicine,Guangzhou,Guangdong 510700)
出处
《按摩与康复医学》
2023年第8期26-29,34,共5页
Chinese Manipulation and Rehabilitation Medicine
基金
广东省中医药局科研项目,编号:20211311
广州市第四批优秀中医临床人才研修项目。
关键词
慢性肺心病
失代偿期
疏利三焦法
中药药氧鼻吸入
肺功能
动脉血气分析
chronic pulmonary heart disease
decompensated period
Shuli Sanjiao method
TCM oxygen nasal inhalation
lung function
arterial blood gas analysis
