摘要
目的:研究妊娠期甲状腺功能减退症的流行病学特征及其影响因素。方法:以回顾性分析为研究方法,使用便利抽样法选取2018年1月—2021年12月于九江市妇幼保健院就诊的1000例妊娠期女性临床资料,统计其中妊娠期甲减发生率,并针对妊娠期甲减的影响因素进行单因素和logistic多因素回归分析。结果:本组1000例妊娠期女性中妊娠期甲减发生率为31.70%,其中临床甲减病例数占所有妊娠期甲减病例数量的33.12%,亚临床甲减病例数占所有妊娠期甲减病例数量的66.88%;年龄≥30岁、体重指数≥24 kg/m^(2)、文化程度为专科及以下水平、有自然流产史、孕期碘摄入量水平过低、合并妊娠期高血压、合并糖尿病患者的妊娠期甲减发生率均更高,差异均有统计学意义(P<0.05);logistic多因素回归分析结果显示年龄≥30岁、文化程度为专科及以下水平、有自然流产史、孕期碘摄入量水平过低、合并有妊娠期高血压、合并有糖尿病是妊娠期甲减发生的独立危险因素(P<0.05)。结论:妊娠期甲减的发生率较高,其中年龄、文化程度、自然流产史、孕期碘摄入量、妊娠期高血压及糖尿病是影响妊娠期甲减发生的重要因素,应根据上述因素采取针对性干预措施。
Objective:To study the epidemiological characteristics and influencing factors of hypothyroidism during pregnancy.Method:A retrospective analysis was used as the study method,and the clinical data of 1,000 pregnant women who received treatment in Jiujiang Maternal and Child Health Hospital from January 2018 to December 2021 were selected using the convenience sampling method,in which the incidence of hypothyroidism in pregnancy was counted,and single-factor and logistic multi-factor regression analyses were performed for the factors influencing hypothyroidism during pregnancy.Result:The incidence of hypothyroidism during pregnancy was 31.70%among 1,000 pregnant women in this group.The number of clinical hypothyroidism cases accounted for 33.12%of all cases of hypothyroidism during pregnancy,and the number of subclinical hypothyroidism cases accounted for 66.88%of all cases of hypothyroidism during pregnancy;the incidences of hypothyroidism during pregnancy were higher in patients with age≥30 years,body mass index≥24 kg/m^(2),education level of specialty or below,history of spontaneous abortion,low iodine intake during pregnancy,hypertension during pregnancy and diabetes mellitus,the differences were statistically significant(P<0.05);logistic multi-factor regression analysis showed that the independent risk factors for hypothyroidism in pregnancy were age≥30 years,education level of specialty or below,history of spontaneous abortion,low iodine intake in pregnancy,hypertension in pregnancy and diabetes mellitus(P<0.05).Conclusion:The incidence of hypothyroidism in pregnancy is high,among which age,education level,history of spontaneous abortion,iodine intake during pregnancy,hypertensive disorders in pregnancy and diabetes mellitus are important factors affecting the occurrence of hypothyroidism during pregnancy,and targeted interventions should be taken according to these factors.
作者
张瑜
ZHANG Yu(Jiujiang Maternal and Child Health Hospital,Jiangxi Province,Jiujiang 332000,China)
出处
《中国医学创新》
CAS
2023年第19期82-86,共5页
Medical Innovation of China
