摘要
目的:探讨负压引流对妇科手术患者术后切口感染及血清炎症介质表达的影响。方法:选取2020年6月-2022年1月佳木斯市中心医院临床收治的妇科手术患者152例为研究对象,随机将患者分成研究组(给予负压引流)和对照组(给予常规处理),每组76例。对两组术后切口感染情况、切口愈合情况、术后瘢痕面积和手术前后血清炎症指标进行观察和比较。结果:研究组术后切口感染5例,切口感染发生率为6.58%,低于对照组(24例,31.58%),差异有统计学意义(P<0.01);研究组术后切口愈合总有效率为98.68%,高于对照组的82.89%,差异有统计学意义(P<0.01);术后4周两组瘢痕面积大小差异无统计学意义(P>0.05),术后8、12、16周,研究组瘢痕面积均小于对照组,差异均有统计学意义(P<0.01);术后1 d,两组各项血清炎症指标比较差异均无统计学意义(P>0.05),术后1周研究组各项血清炎症指标均优于对照组,差异均有统计学意义(P<0.01)。结论:与常规临床措施相比,采用负压引流能够改善妇科手术患者术后切口感染情况,缩小瘢痕面积,改善血清炎症介质表达,是临床应用于妇科开腹手术的理想方式之一。
Objective:To investigate the effect of negative pressure drainage on postoperative wound infection and serum inflammatory mediators in patients undergoing gynecological surgery.Method:From June 2020 to January 2022,152 patients with gynecological surgery in Jiamusi Central Hospital were selected as the research objects.The patients were randomly divided into the study group(given negative pressure drainage)and the control group(given routine treatment),with 76 patients in each group.The wound infection,wound healing,scar area and serum inflammatory indexes before and after operation were observed and compared between the two groups.Result:Five patients in the study group had incision infection after operation,and the incidence of incision infection was 6.58%,lower than 24 patients and 31.58%in the control group,the difference between the two groups was statistically significant(P<0.01);the total effective rate of wound healing in the study group was 98.68%,which was higher than 82.89%in the control group,the difference between the two groups was statistically significant(P<0.01).There was no significant difference in the scar area between the two groups at 4 weeks after operation(P>0.05).At 8,12 and 16 weeks after operation,the scar areas of the study group were smaller than those of the control group,and the differences between the two groups were statistically significant(P<0.01).On the first day after operation,there were no significant differences between the two groups in terms of serum inflammatory indexes(P>0.05).One week after operation,the serum inflammatory indexes of the study group were better than those of the control group,the differences between the two groups were statistically significant(P<0.01).Conclusion:Compared with conventional clinical measures,negative pressure drainage can improve the wound infection,reduce the scar area and improve the expression of serum inflammatory mediators in patients with gynecological surgery.It is one of the ideal methods for clinical application in gynecological open surgery.
作者
白雨昕
BAI Yuxin(Jiamusi Central Hospital,Heilongjiang Province,Jiamusi 154002,China)
出处
《中国医学创新》
CAS
2023年第18期44-48,共5页
Medical Innovation of China
关键词
负压引流
妇科手术
切口感染
炎症介质
Negative pressure drainage
Gynecological surgery
Wound infection
Inflammatory mediators
