摘要
目的探讨健脾清胃汤治疗老年胃食管反流病的效果。方法选取2019年12月至2022年12月我院收治的80例老年胃食管反流病患者,按照抽签法分为观察组与对照组。对照组采用西药治疗,观察组采用健脾清胃汤治疗。比较两组的治疗效果、症状积分及血清指标。结果观察组总有效率为95.00%,高于对照组的72.50%(P<0.05)。治疗后,两组中医证候各项积分均降低,且观察组中医证候各项积分低于对照组(P<0.05)。治疗后,两组的P物质(SP)、降钙素基因相关肽(CGRP)、5-羟色胺(5-HT)水平降低,且观察组SP、CGRP、5-HT水平低于对照组(P<0.05)。结论健脾清胃汤治疗老年胃食管反流病的效果较好,可减轻患者的症状,调节相关神经递质的表达。
Objective To explore the effect of Jianpi Qingwei decoction in the treatment of elderly gastroesophageal reflux disease.Methods 80 elderly patients with gastroesophageal reflux disease admitted to our hospital from December 2019 to December 2022 were selected and divided into observation group and control group according to the method of drawing lots.The control group was treated with Western medicine,while the observation group was treated with Jianpi Qingwei decoction.The treatment effect,symptom scores,and serum indicators were compared between the two groups.Results The total effective rate of the observation group was 95.00%,higher than 72.50%of the control group(P<0.05).After treatment,the scores of TCM syndromes in both groups decreased,and the scores of TCM syndromes in the observation group were lower than those of the control group(P<0.05).After treatment,the SP,CGRP,and 5-HT levels of the two groups decreased,and the SP,CGRP,and 5-HT levels of the observation group were lower than those of the control group(P<0.05).Conclusions Jianpi Qingwei decoction has better treatment effect in the treatment of elderly patients with gastroesophageal reflux disease,which can alleviate the symptoms,and regulate the expression of related neurotransmitters.
作者
郭东红
李成泉
GUO Donghong;LI Chengguan(Department of Traditional Chinese Medicine,Zhengzhou Mingren Hospital,Zhengzhou 450004)
出处
《临床医学工程》
2023年第7期921-922,共2页
Clinical Medicine & Engineering
基金
河南省中医药科学研究专项课题(20-21ZY1031)。
关键词
健脾清胃汤
老年患者
胃食管反流病
Jianpi Qingwei decoction
Elderly patient
Gastroesophageal reflux disease
